BioCosm

Reliability

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How to connect

Add it to any MCP client that supports remote servers.

{
  "mcpServers": {
    "biocosm": {
      "type": "http",
      "url": "https://biocosm-mcp.fly.dev/mcp"
    }
  }
}

13 tools

• search_nodes

  Search BioCosm nodes by name, gene symbol, target, therapeutic area, or company. Results are ranked: exact name/brand matches first, then partial name matches, with a node-type prior (canonical drug/diagnostic nodes rank above gene-target nodes, which rank above ChEMBL…

• get_node

  Get full details for a single BioCosm node: identity and all name aliases, classification, gene targets and mechanism, therapeutic areas, companies, revenue history where available (sparse: ~100 drugs, mostly blockbusters, as annualized quarterly estimates; source links when…

• get_writeup

  Get the full writeup for a BioCosm node, including all sections, citations, structured data, and validation score.

• list_by_therapeutic_area

  List all nodes in a given therapeutic area.

• get_company_portfolio

  Get a company's full drug/diagnostic portfolio from BioCosm.

• get_stats

  Get a high-level overview of the BioCosm database: total nodes, writeups, companies, breakdowns by type/status/domain, validation scores, and recent pipeline runs.

• get_staleness_report

  Get writeup staleness report: overall stats, top stale nodes, data source freshness.

• get_node_freshness

  Get freshness details for a single node: writeup age, enrichment hash match, staleness score, validation score.

• find_by_target

  Find all drugs that target a specific gene/protein.

• find_by_phase

  List drugs/diagnostics at a specific clinical phase.

• find_related

  Find nodes connected to a given node. Three relationship types are derived on-the-fly: - "drug_target": for a drug, the targets it hits (and vice versa for a target node, the drugs that hit it) - "same_company": drugs sharing a company with this node…

• get_pos_score

  Get the Probability of Success estimate for a node, including the base rate, adjustment factors with reasoning, confidence interval, and model version. Returns None for nodes without a PoS score (typically only late-stage pipeline drugs are scored).

• get_coverage

  Report BioCosm's actual data coverage so you never mistake missing data for a real-world zero. An empty or absent field on a node means "not in BioCosm's data," never a true zero. BioCosm is AI-generated and may contain errors.

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