Calc Flipi24

{
  "count": 2,
  "items": [
    {
      "age": 61,
      "b2m_mg_l": 2,
      "citation": {
        "authors": "Maurer MJ, et al.",
        "doi": "10.1200/jco-25-00892",
        "id": "maurer-2025-flipi24",
        "pmid": "41329901",
        "source": "J Clin Oncol. 2026;44(2):117-128",
        "title": "FLIPI24: A Modern Prognostic Model and Clinical Trial Enrichment Tool for Newly Diagnosed Follicular Lymphoma"
      },
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "efs24_event_probability": 0.1156,
      "formula": "flipi24",
      "formula_expression": "efs24_event_probability = 1 - 0.89^exp(lp); lp = 0.01*age60 + 0.038*age_over_75 + 0.364*ldh_uln + 0.159*b2m_mg_l - 0.081*hemoglobin_g_dl + 0.075*wbc_10e9_l - 0.7115; age60 = clamp(age, 60, 90); age_over_75 = min(15, max(0, clamp(age, 0, 90)-75)); ldh_uln clamp 0.5-5; b2m clamp 1-10 mg/L; hemoglobin clamp 8-17 g/dL; wbc clamp 4-11 10^9/L; Maurer 2025 Table S5; S0(24)=0.89; 50% anti-CD20 maintenance is in the 0.7115 centering; risk low if p<=0.10, intermediate if p<=0.15, else high; assumes R-CHOP or B-R-like immunochemotherapy",
      "hemoglobin_g_dl": 13,
      "ldh_uln_ratio": 1,
      "linear_predictor": 0.0525,
      "risk_group": "intermediate",
      "wbc_10e9_l": 7
    },
    {
      "age": 61,
      "b2m_mg_l": 2,
      "citation": {
        "authors": "Maurer MJ, et al.",
        "doi": "10.1200/jco-25-00892",
        "id": "maurer-2025-flipi24",
        "pmid": "41329901",
        "source": "J Clin Oncol. 2026;44(2):117-128",
        "title": "FLIPI24: A Modern Prognostic Model and Clinical Trial Enrichment Tool for Newly Diagnosed Follicular Lymphoma"
      },
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "efs24_event_probability": 0.1156,
      "formula": "flipi24",
      "formula_expression": "efs24_event_probability = 1 - 0.89^exp(lp); lp = 0.01*age60 + 0.038*age_over_75 + 0.364*ldh_uln + 0.159*b2m_mg_l - 0.081*hemoglobin_g_dl + 0.075*wbc_10e9_l - 0.7115; age60 = clamp(age, 60, 90); age_over_75 = min(15, max(0, clamp(age, 0, 90)-75)); ldh_uln clamp 0.5-5; b2m clamp 1-10 mg/L; hemoglobin clamp 8-17 g/dL; wbc clamp 4-11 10^9/L; Maurer 2025 Table S5; S0(24)=0.89; 50% anti-CD20 maintenance is in the 0.7115 centering; risk low if p<=0.10, intermediate if p<=0.15, else high; assumes R-CHOP or B-R-like immunochemotherapy",
      "hemoglobin_g_dl": 13,
      "ldh_uln_ratio": 1,
      "linear_predictor": 0.0525,
      "risk_group": "intermediate",
      "wbc_10e9_l": 7
    }
  ],
  "path": "/api/calc/flipi24"
}

# bash or zsh: see the payment challenge. Nothing is charged.
curl -sS -g -i -X POST 'https://api.magentlab.com/api/calc/flipi24' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"age":61,"b2m_mg_l":2,"hemoglobin_g_dl":13,"ldh_uln_ratio":1,"wbc_10e9_l":7},{"age":61,"b2m_mg_l":2,"hemoglobin_g_dl":13,"ldh_uln_ratio":1,"wbc_10e9_l":7}]}'

# x402 v2 sends the challenge base64-encoded in the PAYMENT-REQUIRED header (v1 sends it in the body).
# To read the header:
curl -sS -g -o /dev/null -D - -X POST 'https://api.magentlab.com/api/calc/flipi24' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"age":61,"b2m_mg_l":2,"hemoglobin_g_dl":13,"ldh_uln_ratio":1,"wbc_10e9_l":7},{"age":61,"b2m_mg_l":2,"hemoglobin_g_dl":13,"ldh_uln_ratio":1,"wbc_10e9_l":7}]}' \
  | grep -i '^payment-required:' | cut -d' ' -f2 | tr -d '\r' | base64 --decode

// npm i @x402/fetch @x402/evm viem
import { wrapFetchWithPayment, x402Client } from "@x402/fetch";
import { registerExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";

// Pays at most $0.007 per call.
const client = new x402Client().setSpendControls({ maxAmountPerPayment: "$0.007" });
registerExactEvmScheme(client, { signer: privateKeyToAccount(process.env.EVM_PRIVATE_KEY) });
const pay = wrapFetchWithPayment(fetch, client);

// Not sure it's safe to pay? ToolVet checks it first for $0.005. Pay for that from a separate
// client: this one is capped at $0.007 per payment. GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Fapi.magentlab.com%2Fapi%2Fcalc%2Fflipi24&method=POST
const res = await pay("https://api.magentlab.com/api/calc/flipi24", {
  method: "POST",
  headers: { "content-type": "application/json" },
  body: JSON.stringify({
    "items": [
      {
        "age": 61,
        "b2m_mg_l": 2,
        "hemoglobin_g_dl": 13,
        "ldh_uln_ratio": 1,
        "wbc_10e9_l": 7
      },
      {
        "age": 61,
        "b2m_mg_l": 2,
        "hemoglobin_g_dl": 13,
        "ldh_uln_ratio": 1,
        "wbc_10e9_l": 7
      }
    ]
  }),
});
console.log(res.status, await res.text());

# pip install "x402[requests,evm]"
import os
from eth_account import Account
from x402 import x402ClientSync
from x402.http.clients import x402_requests
from x402.mechanisms.evm import EthAccountSigner
from x402.mechanisms.evm.exact.register import register_exact_evm_client

# Pays at most $0.007 per call.
client = x402ClientSync().set_spend_controls({"max_amount_per_payment": "$0.007"})
register_exact_evm_client(client, EthAccountSigner(Account.from_key(os.environ["EVM_PRIVATE_KEY"])))

with x402_requests(client) as session:
    res = session.post(
        "https://api.magentlab.com/api/calc/flipi24",
        json={
            "items": [
                {
                    "age": 61,
                    "b2m_mg_l": 2,
                    "hemoglobin_g_dl": 13,
                    "ldh_uln_ratio": 1,
                    "wbc_10e9_l": 7,
                },
                {
                    "age": 61,
                    "b2m_mg_l": 2,
                    "hemoglobin_g_dl": 13,
                    "ldh_uln_ratio": 1,
                    "wbc_10e9_l": 7,
                },
            ],
        },
    )
    print(res.status_code, res.text)