Calc Gipss
by magent in Other
Tefferi 2018 GIPSS for primary myelofibrosis: karyotype (favorable 0, unfavorable 1, VHR 2; caller assigns the three-tier class), absence of type 1/like CALR 1, ASXL1 1, SRSF2 1, U2AF1Q157 1 (not S34); max 6. Low 0, intermediate_1 1, intermediate_2 2, high ≥3. Published median (5-year) survivals 26.4 y (94%), 8.0 y (73%), 4.2 y (40%), 2 y (14%). Not DIPSS or MIPSS70-plus. magent does not karyotype or sequence.
https://api.magentlab.com/api/calc/gipss- Price
- $0.007
- per call in USDC
- Uptime
- 94.1%
- last 30 days
- Response time
- 159 ms
- 487 ms slowest 5%
- Last check
- Failed
- 4 h ago, next any minute now
Reliability
Latest check failed 4 h ago: Timed out
Status and outage history · Atom feed · Watch with other listings
How to call it
POST https://api.magentlab.com/api/calc/gipss
Each call costs $0.007 in USDC on Base, paid with the request over x402.
Run a free test callOne unpaid request, the way an agent sends it. You see the payment challenge it gets back. Nothing is charged.
Example request
From the listing.
POST https://api.magentlab.com/api/calc/gipss
content-type: application/json
{
"items": [
{
"asxl1_mutated": false,
"calr_type1_like": true,
"karyotype": "favorable",
"srsf2_mutated": false,
"u2af1_q157_mutated": false
},
{
"asxl1_mutated": false,
"calr_type1_like": true,
"karyotype": "favorable",
"srsf2_mutated": false,
"u2af1_q157_mutated": false
}
]
}Parameters
| Parameter | Type | Required | Description |
|---|---|---|---|
items | array of object | Yes |
Example response
The provider's example. We can't check it without paying.
Example response, 108 lines
{
"count": 2,
"items": [
{
"asxl1_mutated": false,
"calr_type1_like": true,
"citation": {
"authors": "Tefferi A, Guglielmelli P, Nicolosi M, Mannelli F, Mudireddy M, Bartalucci N, Finke CM, Lasho TL, Hanson CA, Ketterling RP, Begna KH, Gangat N, Pardanani A, Vannucchi AM",
"doi": "10.1038/s41375-018-0107-z",
"id": "tefferi-2018",
"pmid": "29654267",
"source": "Leukemia. 2018;32(7):1631-1642",
"title": "GIPSS: genetically inspired prognostic scoring system for primary myelofibrosis"
},
"components": [
{
"factor": "karyotype",
"points": 0,
"present": false,
"value": "favorable"
},
{
"factor": "absence_of_calr_type1_like",
"points": 0,
"present": false
},
{
"factor": "asxl1_mutated",
"points": 0,
"present": false
},
{
"factor": "srsf2_mutated",
"points": 0,
"present": false
},
{
"factor": "u2af1_q157_mutated",
"points": 0,
"present": false
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"five_year_survival_percent": 94,
"formula": "gipss",
"formula_expression": "GIPSS = karyotype (favorable 0, unfavorable 1, vhr 2) + absence of type 1/like CALR 1 + asxl1_mutated 1 + srsf2_mutated 1 + u2af1_q157_mutated 1; Tefferi 2018; max 6; low 0, intermediate_1 1, intermediate_2 2, high ≥3",
"karyotype": "favorable",
"max_score": 6,
"median_survival_years": 26.4,
"risk_group": "low",
"score": 0,
"srsf2_mutated": false,
"u2af1_q157_mutated": false
},
{
"asxl1_mutated": false,
"calr_type1_like": true,
"citation": {
"authors": "Tefferi A, Guglielmelli P, Nicolosi M, Mannelli F, Mudireddy M, Bartalucci N, Finke CM, Lasho TL, Hanson CA, Ketterling RP, Begna KH, Gangat N, Pardanani A, Vannucchi AM",
"doi": "10.1038/s41375-018-0107-z",
"id": "tefferi-2018",
"pmid": "29654267",
"source": "Leukemia. 2018;32(7):1631-1642",
"title": "GIPSS: genetically inspired prognostic scoring system for primary myelofibrosis"
},
"components": [
{
"factor": "karyotype",
"points": 0,
"present": false,
"value": "favorable"
},
{
"factor": "absence_of_calr_type1_like",
"points": 0,
"present": false
},
{
"factor": "asxl1_mutated",
"points": 0,
"present": false
},
{
"factor": "srsf2_mutated",
"points": 0,
"present": false
},
{
"factor": "u2af1_q157_mutated",
"points": 0,
"present": false
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"five_year_survival_percent": 94,
"formula": "gipss",
"formula_expression": "GIPSS = karyotype (favorable 0, unfavorable 1, vhr 2) + absence of type 1/like CALR 1 + asxl1_mutated 1 + srsf2_mutated 1 + u2af1_q157_mutated 1; Tefferi 2018; max 6; low 0, intermediate_1 1, intermediate_2 2, high ≥3",
"karyotype": "favorable",
"max_score": 6,
"median_survival_years": 26.4,
"risk_group": "low",
"score": 0,
"srsf2_mutated": false,
"u2af1_q157_mutated": false
}
],
"path": "/api/calc/gipss"
}Call it from code
The curl command shows the payment challenge. The JavaScript and Python versions pay and call, and never pay more than $0.007.
curl: see the payment challenge
# bash or zsh: see the payment challenge. Nothing is charged.
curl -sS -g -i -X POST 'https://api.magentlab.com/api/calc/gipss' \
-H 'content-type: application/json' \
--data-raw '{"items":[{"asxl1_mutated":false,"calr_type1_like":true,"karyotype":"favorable","srsf2_mutated":false,"u2af1_q157_mutated":false},{"asxl1_mutated":false,"calr_type1_like":true,"karyotype":"favorable","srsf2_mutated":false,"u2af1_q157_mutated":false}]}'
# x402 v2 sends the challenge base64-encoded in the PAYMENT-REQUIRED header (v1 sends it in the body).
# To read the header:
curl -sS -g -o /dev/null -D - -X POST 'https://api.magentlab.com/api/calc/gipss' \
-H 'content-type: application/json' \
--data-raw '{"items":[{"asxl1_mutated":false,"calr_type1_like":true,"karyotype":"favorable","srsf2_mutated":false,"u2af1_q157_mutated":false},{"asxl1_mutated":false,"calr_type1_like":true,"karyotype":"favorable","srsf2_mutated":false,"u2af1_q157_mutated":false}]}' \
| grep -i '^payment-required:' | cut -d' ' -f2 | tr -d '\r' | base64 --decodeJavaScript: pay and call
// npm i @x402/fetch @x402/evm viem
import { wrapFetchWithPayment, x402Client } from "@x402/fetch";
import { registerExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";
// Pays at most $0.007 per call.
const client = new x402Client().setSpendControls({ maxAmountPerPayment: "$0.007" });
registerExactEvmScheme(client, { signer: privateKeyToAccount(process.env.EVM_PRIVATE_KEY) });
const pay = wrapFetchWithPayment(fetch, client);
// Not sure it's safe to pay? ToolVet checks it first for $0.005. Pay for that from a separate
// client: this one is capped at $0.007 per payment. GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Fapi.magentlab.com%2Fapi%2Fcalc%2Fgipss&method=POST
const res = await pay("https://api.magentlab.com/api/calc/gipss", {
method: "POST",
headers: { "content-type": "application/json" },
body: JSON.stringify({
"items": [
{
"asxl1_mutated": false,
"calr_type1_like": true,
"karyotype": "favorable",
"srsf2_mutated": false,
"u2af1_q157_mutated": false
},
{
"asxl1_mutated": false,
"calr_type1_like": true,
"karyotype": "favorable",
"srsf2_mutated": false,
"u2af1_q157_mutated": false
}
]
}),
});
console.log(res.status, await res.text());Python: pay and call
# pip install "x402[requests,evm]"
import os
from eth_account import Account
from x402 import x402ClientSync
from x402.http.clients import x402_requests
from x402.mechanisms.evm import EthAccountSigner
from x402.mechanisms.evm.exact.register import register_exact_evm_client
# Pays at most $0.007 per call.
client = x402ClientSync().set_spend_controls({"max_amount_per_payment": "$0.007"})
register_exact_evm_client(client, EthAccountSigner(Account.from_key(os.environ["EVM_PRIVATE_KEY"])))
with x402_requests(client) as session:
res = session.post(
"https://api.magentlab.com/api/calc/gipss",
json={
"items": [
{
"asxl1_mutated": False,
"calr_type1_like": True,
"karyotype": "favorable",
"srsf2_mutated": False,
"u2af1_q157_mutated": False,
},
{
"asxl1_mutated": False,
"calr_type1_like": True,
"karyotype": "favorable",
"srsf2_mutated": False,
"u2af1_q157_mutated": False,
},
],
},
)
print(res.status_code, res.text)Security scan
1 finding
- Charges more than its listed price in payment
Listed at $0.005, charges $0.007
Recent checks
| When | Result | HTTP | Time | Price |
|---|---|---|---|---|
| 4 h ago | Timed out | - | - | - |
| 8 h ago | Timed out | - | - | - |
| 13 h ago | Passed | 402 | 137 ms | $0.007 |
| 18 h ago | Passed | 402 | 153 ms | $0.007 |
| 23 h ago | Passed | 402 | 214 ms | $0.007 |
Show 10 older checks
| 27 h ago | Passed | 402 | 244 ms | $0.007 |
| 32 h ago | Passed | 402 | 254 ms | $0.007 |
| 36 h ago | Passed | 402 | 258 ms | $0.007 |
| 41 h ago | Passed | 402 | 293 ms | $0.007 |
| 45 h ago | Passed | 402 | 247 ms | $0.007 |
| 2 days ago | Passed | 402 | 983 ms | $0.007 |
| 2 days ago | Passed | 402 | 147 ms | $0.007 |
| 2 days ago | Passed | 402 | 487 ms | $0.007 |
| 3 days ago | Passed | 402 | 188 ms | $0.007 |
| 3 days ago | Passed | 402 | 348 ms | $0.007 |
History
| 11 Oct 2026 | Price changed from $0.005 to $0.007 |