73trust / 100

Calc Gipss

by magent in Other

x402 APIFailing, checked 48 min ago

Tefferi 2018 GIPSS for primary myelofibrosis: karyotype (favorable 0, unfavorable 1, VHR 2; caller assigns the three-tier class), absence of type 1/like CALR 1, ASXL1 1, SRSF2 1, U2AF1Q157 1 (not S34); max 6. Low 0, intermediate_1 1, intermediate_2 2, high ≥3. Published median (5-year) survivals 26.4 y (94%), 8.0 y (73%), 4.2 y (40%), 2 y (14%). Not DIPSS or MIPSS70-plus. magent does not karyotype or sequence.

GET
https://api.magentlab.com/api/calc/gipss
Price
$0.005
per call in USDC
Uptime
92.3%
last 30 days
Response time
168 ms
429 ms slowest 5%
Last check
Failed
48 min ago, next in 5 h

Run a free test callHow to call it

Reliability

All checks passedSome failedAll failedNot checked

Latest check failed 48 min ago: Timed out

Status and outage history · Atom feed · Watch with other listings

How to call it

GET https://api.magentlab.com/api/calc/gipss

Each call costs $0.005 in USDC on Base, paid with the request over x402.

Run a free test callOne unpaid request, the way an agent sends it. You see the payment challenge it gets back. Nothing is charged.

Example request

From the listing.

GET https://api.magentlab.com/api/calc/gipss?asxl1_mutated=false&calr_type1_like=true&karyotype=favorable&srsf2_mutated=false&u2af1_q157_mutated=false

Parameters

ParameterTypeRequiredDescription
asxl1_mutatedbooleanYesASXL1 mutation as assigned by the caller (Tefferi 2018). true scores 1. magent does not sequence.
calr_type1_likebooleanYesPresence of a type 1/like CALR mutation as assigned by the caller (Tefferi 2018). false (absence) scores 1. true scores 0. Type 2/like CALR, JAK2, MPL, and triple-negative are absence of type 1/like CALR. magent does not sequence.
karyotypestringYesTefferi 2018 revised three-tier karyotype as assigned by the caller (mutually exclusive). favorable is a normal karyotype or sole 13q−, +9, 20q−, chromosome 1 translocation/duplication, or sex chromosome abnormality including −Y and scores 0. unfavorable is all other abnormalities and scores 1. vhr… One of: favorable, unfavorable, vhr.
srsf2_mutatedbooleanYesSRSF2 mutation as assigned by the caller (Tefferi 2018). true scores 1. magent does not sequence.
u2af1_q157_mutatedbooleanYesU2AF1 Q157 mutation (Q157P or Q157R) as assigned by the caller (Tefferi 2018). true scores 1. U2AF1 S34 does not score. magent does not sequence.

Example response

The provider's example. We can't check it without paying.

Example response, 51 lines
{
  "asxl1_mutated": false,
  "calr_type1_like": true,
  "citation": {
    "authors": "Tefferi A, Guglielmelli P, Nicolosi M, Mannelli F, Mudireddy M, Bartalucci N, Finke CM, Lasho TL, Hanson CA, Ketterling RP, Begna KH, Gangat N, Pardanani A, Vannucchi AM",
    "doi": "10.1038/s41375-018-0107-z",
    "id": "tefferi-2018",
    "pmid": "29654267",
    "source": "Leukemia. 2018;32(7):1631-1642",
    "title": "GIPSS: genetically inspired prognostic scoring system for primary myelofibrosis"
  },
  "components": [
    {
      "factor": "karyotype",
      "points": 0,
      "present": false,
      "value": "favorable"
    },
    {
      "factor": "absence_of_calr_type1_like",
      "points": 0,
      "present": false
    },
    {
      "factor": "asxl1_mutated",
      "points": 0,
      "present": false
    },
    {
      "factor": "srsf2_mutated",
      "points": 0,
      "present": false
    },
    {
      "factor": "u2af1_q157_mutated",
      "points": 0,
      "present": false
    }
  ],
  "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
  "five_year_survival_percent": 94,
  "formula": "gipss",
  "formula_expression": "GIPSS = karyotype (favorable 0, unfavorable 1, vhr 2) + absence of type 1/like CALR 1 + asxl1_mutated 1 + srsf2_mutated 1 + u2af1_q157_mutated 1; Tefferi 2018; max 6; low 0, intermediate_1 1, intermediate_2 2, high ≥3",
  "karyotype": "favorable",
  "max_score": 6,
  "median_survival_years": 26.4,
  "risk_group": "low",
  "score": 0,
  "srsf2_mutated": false,
  "u2af1_q157_mutated": false
}

Call it from code

The curl command shows the payment challenge. The JavaScript and Python versions pay and call, and never pay more than $0.005.

curl: see the payment challenge
# bash or zsh: see the payment challenge. Nothing is charged.
curl -sS -g -i 'https://api.magentlab.com/api/calc/gipss?asxl1_mutated=false&calr_type1_like=true&karyotype=favorable&srsf2_mutated=false&u2af1_q157_mutated=false'

# x402 v2 sends the challenge base64-encoded in the PAYMENT-REQUIRED header (v1 sends it in the body).
# To read the header:
curl -sS -g -o /dev/null -D - 'https://api.magentlab.com/api/calc/gipss?asxl1_mutated=false&calr_type1_like=true&karyotype=favorable&srsf2_mutated=false&u2af1_q157_mutated=false' \
  | grep -i '^payment-required:' | cut -d' ' -f2 | tr -d '\r' | base64 --decode
JavaScript: pay and call
// npm i @x402/fetch @x402/evm viem
import { wrapFetchWithPayment, x402Client } from "@x402/fetch";
import { registerExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";

// Pays at most $0.005 per call.
const client = new x402Client().setSpendControls({ maxAmountPerPayment: "$0.005" });
registerExactEvmScheme(client, { signer: privateKeyToAccount(process.env.EVM_PRIVATE_KEY) });
const pay = wrapFetchWithPayment(fetch, client);

// Not sure it's safe to pay? ToolVet checks it first for $0.005. Pay for that from a separate
// client: this one is capped at $0.005 per payment. GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Fapi.magentlab.com%2Fapi%2Fcalc%2Fgipss
const res = await pay("https://api.magentlab.com/api/calc/gipss?asxl1_mutated=false&calr_type1_like=true&karyotype=favorable&srsf2_mutated=false&u2af1_q157_mutated=false");
console.log(res.status, await res.text());
Python: pay and call
# pip install "x402[requests,evm]"
import os
from eth_account import Account
from x402 import x402ClientSync
from x402.http.clients import x402_requests
from x402.mechanisms.evm import EthAccountSigner
from x402.mechanisms.evm.exact.register import register_exact_evm_client

# Pays at most $0.005 per call.
client = x402ClientSync().set_spend_controls({"max_amount_per_payment": "$0.005"})
register_exact_evm_client(client, EthAccountSigner(Account.from_key(os.environ["EVM_PRIVATE_KEY"])))

with x402_requests(client) as session:
    res = session.get("https://api.magentlab.com/api/calc/gipss?asxl1_mutated=false&calr_type1_like=true&karyotype=favorable&srsf2_mutated=false&u2af1_q157_mutated=false")
    print(res.status_code, res.text)

Security scan

No findings

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Recent checks

WhenResultHTTPTimePrice
48 min agoTimed out---
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33 h agoPassed402275 ms$0.005
43 h agoPassed402168 ms$0.005
Show 8 older checks
2 days agoPassed402141 ms$0.005
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3 days agoPassed402139 ms$0.005
4 days agoPassed402150 ms$0.005
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5 days agoPassed402289 ms$0.005
5 days agoPassed402153 ms$0.005