65trust / 100

Calc Hfa Icos Anthracycline

x402 APIFailing, checked 17 min ago

Lyon 2020 HFA-ICOS baseline cardiovascular risk before anthracycline chemotherapy. Returns risk_level low, medium, high, or very_high from published Very high, High, Medium 2, and Medium 1 factors, plus medium_points and the paper's expert-opinion cardiotoxicity_guide. Age and LVEF use the highest matching printed band only. Caller assigns labs and BMI >30. magent does not examine the patient or read imaging. Not a medical device or treatment order.

POST

https://api.magentlab.com/api/calc/hfa_icos_anthracycline

Price: $0.007; per call in USDC
Uptime: 88.9%; last 30 days
Response time: 209 ms; 502 ms slowest 5%
Last check: Failed; 17 min ago, next in 38 min

Run a free test call How to call it

Reliability

All checks passedSome failedAll failedNot checked

Latest check failed 17 min ago: Timed out

Status and outage history · Atom feed · Watch with other listings

How to call it

POST https://api.magentlab.com/api/calc/hfa_icos_anthracycline

Each call costs $0.007 in USDC on Base, paid with the request over x402.

Run a free test callOne unpaid request, the way an agent sends it. You see the payment challenge it gets back. Nothing is charged.

Example request

From the listing.

POST https://api.magentlab.com/api/calc/hfa_icos_anthracycline
content-type: application/json

{
  "items": [
    {
      "age_years": 50,
      "ckd": false,
      "current_or_significant_smoker": false,
      "diabetes": false,
      "elevated_bnp": false,
      "elevated_troponin": false,
      "heart_failure_or_cardiomyopathy": false,
      "hypertension": false,
      "lvef_percent": 60,
      "mi_or_coronary_revascularization": false,
      "obesity": false,
      "previous_anthracycline": false,
      "previous_non_anthracycline_chemo": false,
      "prior_left_chest_or_mediastinal_rt": false,
      "severe_valvular_heart_disease": false,
      "stable_angina": false
    },
    {
      "age_years": 50,
      "ckd": false,
      "current_or_significant_smoker": false,
      "diabetes": false,
      "elevated_bnp": false,
      "elevated_troponin": false,
      "heart_failure_or_cardiomyopathy": false,
      "hypertension": false,
      "lvef_percent": 60,
      "mi_or_coronary_revascularization": false,
      "obesity": false,
      "previous_anthracycline": false,
      "previous_non_anthracycline_chemo": false,
      "prior_left_chest_or_mediastinal_rt": false,
      "severe_valvular_heart_disease": false,
      "stable_angina": false
    }
  ]
}

Parameters

Parameter	Type	Required	Description
`items`	array of object	Yes

Example response

The provider's example. We can't check it without paying.

Example response, 242 lines

{
  "count": 2,
  "items": [
    {
      "age_years": 50,
      "cardiotoxicity_guide": "<2%",
      "citation": {
        "authors": "Lyon AR, Dent S, Stanway S, et al.",
        "doi": "10.1002/ejhf.1920",
        "id": "lyon-2020",
        "pmid": "32458582",
        "source": "Eur J Heart Fail. 2020;22(11):1945-1960",
        "title": "Baseline cardiovascular risk assessment in cancer patients scheduled to receive cardiotoxic cancer therapies: a position statement and new risk assessment tools from the Cardio-Oncology Study Group of the Heart Failure Association of the European Society of Cardiology in collaboration with the International Cardio-Oncology Society"
      },
      "components": [
        {
          "factor": "heart_failure_or_cardiomyopathy",
          "points": 0,
          "present": false,
          "tier": "very_high"
        },
        {
          "factor": "severe_valvular_heart_disease",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "mi_or_coronary_revascularization",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "stable_angina",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "previous_anthracycline",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "prior_left_chest_or_mediastinal_rt",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "elevated_troponin",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "elevated_bnp",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "hypertension",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "diabetes",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "ckd",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "previous_non_anthracycline_chemo",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "current_or_significant_smoker",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "obesity",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "age_years",
          "points": 0,
          "present": false,
          "tier": "none",
          "value": 50
        },
        {
          "factor": "lvef_percent",
          "points": 0,
          "present": false,
          "tier": "none",
          "value": 60
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "formula": "hfa_icos_anthracycline",
      "formula_expression": "very_high if heart_failure_or_cardiomyopathy; else high if any High factor (severe_valvular_heart_disease, mi_or_coronary_revascularization, stable_angina, lvef_percent<50, age_years>=80, previous_anthracycline, prior_left_chest_or_mediastinal_rt) OR medium_points>=5; else medium if medium_points in 2..4; else low (no factors or one Medium 1). medium_points sums Medium 1 (=1: elevated_troponin, elevated_bnp, hypertension, diabetes, ckd, previous_non_anthracycline_chemo, current_or_significant_smoker, obesity) and Medium 2 (=2: lvef_percent 50-54, age_years 65-79) only. Age and LVEF use the highest matching printed band. Lyon 2020 HFA-ICOS anthracycline table. cardiotoxicity_guide is that paper's expert-opinion guide: low <2%, medium 2-9%, high 10-19%, very high >=20%",
      "lvef_percent": 60,
      "medium_points": 0,
      "risk_level": "low"
    },
    {
      "age_years": 50,
      "cardiotoxicity_guide": "<2%",
      "citation": {
        "authors": "Lyon AR, Dent S, Stanway S, et al.",
        "doi": "10.1002/ejhf.1920",
        "id": "lyon-2020",
        "pmid": "32458582",
        "source": "Eur J Heart Fail. 2020;22(11):1945-1960",
        "title": "Baseline cardiovascular risk assessment in cancer patients scheduled to receive cardiotoxic cancer therapies: a position statement and new risk assessment tools from the Cardio-Oncology Study Group of the Heart Failure Association of the European Society of Cardiology in collaboration with the International Cardio-Oncology Society"
      },
      "components": [
        {
          "factor": "heart_failure_or_cardiomyopathy",
          "points": 0,
          "present": false,
          "tier": "very_high"
        },
        {
          "factor": "severe_valvular_heart_disease",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "mi_or_coronary_revascularization",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "stable_angina",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "previous_anthracycline",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "prior_left_chest_or_mediastinal_rt",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "elevated_troponin",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "elevated_bnp",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "hypertension",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "diabetes",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "ckd",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "previous_non_anthracycline_chemo",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "current_or_significant_smoker",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "obesity",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "age_years",
          "points": 0,
          "present": false,
          "tier": "none",
          "value": 50
        },
        {
          "factor": "lvef_percent",
          "points": 0,
          "present": false,
          "tier": "none",
          "value": 60
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "formula": "hfa_icos_anthracycline",
      "formula_expression": "very_high if heart_failure_or_cardiomyopathy; else high if any High factor (severe_valvular_heart_disease, mi_or_coronary_revascularization, stable_angina, lvef_percent<50, age_years>=80, previous_anthracycline, prior_left_chest_or_mediastinal_rt) OR medium_points>=5; else medium if medium_points in 2..4; else low (no factors or one Medium 1). medium_points sums Medium 1 (=1: elevated_troponin, elevated_bnp, hypertension, diabetes, ckd, previous_non_anthracycline_chemo, current_or_significant_smoker, obesity) and Medium 2 (=2: lvef_percent 50-54, age_years 65-79) only. Age and LVEF use the highest matching printed band. Lyon 2020 HFA-ICOS anthracycline table. cardiotoxicity_guide is that paper's expert-opinion guide: low <2%, medium 2-9%, high 10-19%, very high >=20%",
      "lvef_percent": 60,
      "medium_points": 0,
      "risk_level": "low"
    }
  ],
  "path": "/api/calc/hfa_icos_anthracycline"
}

Call it from code

The curl command shows the payment challenge. The JavaScript and Python versions pay and call, and never pay more than $0.007.

curl: see the payment challenge

# bash or zsh: see the payment challenge. Nothing is charged.
curl -sS -g -i -X POST 'https://api.magentlab.com/api/calc/hfa_icos_anthracycline' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"age_years":50,"ckd":false,"current_or_significant_smoker":false,"diabetes":false,"elevated_bnp":false,"elevated_troponin":false,"heart_failure_or_cardiomyopathy":false,"hypertension":false,"lvef_percent":60,"mi_or_coronary_revascularization":false,"obesity":false,"previous_anthracycline":false,"previous_non_anthracycline_chemo":false,"prior_left_chest_or_mediastinal_rt":false,"severe_valvular_heart_disease":false,"stable_angina":false},{"age_years":50,"ckd":false,"current_or_significant_smoker":false,"diabetes":false,"elevated_bnp":false,"elevated_troponin":false,"heart_failure_or_cardiomyopathy":false,"hypertension":false,"lvef_percent":60,"mi_or_coronary_revascularization":false,"obesity":false,"previous_anthracycline":false,"previous_non_anthracycline_chemo":false,"prior_left_chest_or_mediastinal_rt":false,"severe_valvular_heart_disease":false,"stable_angina":false}]}'

# x402 v2 sends the challenge base64-encoded in the PAYMENT-REQUIRED header (v1 sends it in the body).
# To read the header:
curl -sS -g -o /dev/null -D - -X POST 'https://api.magentlab.com/api/calc/hfa_icos_anthracycline' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"age_years":50,"ckd":false,"current_or_significant_smoker":false,"diabetes":false,"elevated_bnp":false,"elevated_troponin":false,"heart_failure_or_cardiomyopathy":false,"hypertension":false,"lvef_percent":60,"mi_or_coronary_revascularization":false,"obesity":false,"previous_anthracycline":false,"previous_non_anthracycline_chemo":false,"prior_left_chest_or_mediastinal_rt":false,"severe_valvular_heart_disease":false,"stable_angina":false},{"age_years":50,"ckd":false,"current_or_significant_smoker":false,"diabetes":false,"elevated_bnp":false,"elevated_troponin":false,"heart_failure_or_cardiomyopathy":false,"hypertension":false,"lvef_percent":60,"mi_or_coronary_revascularization":false,"obesity":false,"previous_anthracycline":false,"previous_non_anthracycline_chemo":false,"prior_left_chest_or_mediastinal_rt":false,"severe_valvular_heart_disease":false,"stable_angina":false}]}' \
  | grep -i '^payment-required:' | cut -d' ' -f2 | tr -d '\r' | base64 --decode

JavaScript: pay and call

// npm i @x402/fetch @x402/evm viem
import { wrapFetchWithPayment, x402Client } from "@x402/fetch";
import { registerExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";

// Pays at most $0.007 per call.
const client = new x402Client().setSpendControls({ maxAmountPerPayment: "$0.007" });
registerExactEvmScheme(client, { signer: privateKeyToAccount(process.env.EVM_PRIVATE_KEY) });
const pay = wrapFetchWithPayment(fetch, client);

// Not sure it's safe to pay? ToolVet checks it first for $0.005. Pay for that from a separate
// client: this one is capped at $0.007 per payment. GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Fapi.magentlab.com%2Fapi%2Fcalc%2Fhfa_icos_anthracycline&method=POST
const res = await pay("https://api.magentlab.com/api/calc/hfa_icos_anthracycline", {
  method: "POST",
  headers: { "content-type": "application/json" },
  body: JSON.stringify({
    "items": [
      {
        "age_years": 50,
        "ckd": false,
        "current_or_significant_smoker": false,
        "diabetes": false,
        "elevated_bnp": false,
        "elevated_troponin": false,
        "heart_failure_or_cardiomyopathy": false,
        "hypertension": false,
        "lvef_percent": 60,
        "mi_or_coronary_revascularization": false,
        "obesity": false,
        "previous_anthracycline": false,
        "previous_non_anthracycline_chemo": false,
        "prior_left_chest_or_mediastinal_rt": false,
        "severe_valvular_heart_disease": false,
        "stable_angina": false
      },
      {
        "age_years": 50,
        "ckd": false,
        "current_or_significant_smoker": false,
        "diabetes": false,
        "elevated_bnp": false,
        "elevated_troponin": false,
        "heart_failure_or_cardiomyopathy": false,
        "hypertension": false,
        "lvef_percent": 60,
        "mi_or_coronary_revascularization": false,
        "obesity": false,
        "previous_anthracycline": false,
        "previous_non_anthracycline_chemo": false,
        "prior_left_chest_or_mediastinal_rt": false,
        "severe_valvular_heart_disease": false,
        "stable_angina": false
      }
    ]
  }),
});
console.log(res.status, await res.text());

Python: pay and call

# pip install "x402[requests,evm]"
import os
from eth_account import Account
from x402 import x402ClientSync
from x402.http.clients import x402_requests
from x402.mechanisms.evm import EthAccountSigner
from x402.mechanisms.evm.exact.register import register_exact_evm_client

# Pays at most $0.007 per call.
client = x402ClientSync().set_spend_controls({"max_amount_per_payment": "$0.007"})
register_exact_evm_client(client, EthAccountSigner(Account.from_key(os.environ["EVM_PRIVATE_KEY"])))

with x402_requests(client) as session:
    res = session.post(
        "https://api.magentlab.com/api/calc/hfa_icos_anthracycline",
        json={
            "items": [
                {
                    "age_years": 50,
                    "ckd": False,
                    "current_or_significant_smoker": False,
                    "diabetes": False,
                    "elevated_bnp": False,
                    "elevated_troponin": False,
                    "heart_failure_or_cardiomyopathy": False,
                    "hypertension": False,
                    "lvef_percent": 60,
                    "mi_or_coronary_revascularization": False,
                    "obesity": False,
                    "previous_anthracycline": False,
                    "previous_non_anthracycline_chemo": False,
                    "prior_left_chest_or_mediastinal_rt": False,
                    "severe_valvular_heart_disease": False,
                    "stable_angina": False,
                },
                {
                    "age_years": 50,
                    "ckd": False,
                    "current_or_significant_smoker": False,
                    "diabetes": False,
                    "elevated_bnp": False,
                    "elevated_troponin": False,
                    "heart_failure_or_cardiomyopathy": False,
                    "hypertension": False,
                    "lvef_percent": 60,
                    "mi_or_coronary_revascularization": False,
                    "obesity": False,
                    "previous_anthracycline": False,
                    "previous_non_anthracycline_chemo": False,
                    "prior_left_chest_or_mediastinal_rt": False,
                    "severe_valvular_heart_disease": False,
                    "stable_angina": False,
                },
            ],
        },
    )
    print(res.status_code, res.text)

Security scan

1 finding

Charges more than its listed price in payment
Listed at $0.005, charges $0.007

Recent checks

When	Result	HTTP	Time	Price
17 min ago	Timed out	-	-	-
6 h ago	Timed out	-	-	-
11 h ago	Timed out	-	-	-
16 h ago	Timed out	-	-	-
20 h ago	Passed	402	163 ms	$0.007

Show 10 older checks

25 h ago	Passed	402	209 ms	$0.007
30 h ago	Passed	402	175 ms	$0.007
35 h ago	Passed	402	336 ms	$0.007
39 h ago	Passed	402	310 ms	$0.007
44 h ago	Passed	402	153 ms	$0.007
2 days ago	Passed	402	506 ms	$0.007
2 days ago	Passed	402	180 ms	$0.007
2 days ago	Passed	402	445 ms	$0.007
3 days ago	Passed	402	155 ms	$0.007
3 days ago	Passed	402	179 ms	$0.007

History

11 Oct 2026	Price changed from $0.005 to $0.007

Trust score 65/ 100

Availability (30-day uptime)		27 / 30
Valid x402 challenge		15 / 15
Response time		10 / 10
Real paying agents (30 days)		3 / 15
Charges what it lists		0 / 10
Security scan		10 / 10
Verified owner		0 / 10

How the score works

Payment terms

Price: $0.007 per call
Listed at: $0.005 (charges more)
Token: USDC
Networks: Base
Pays to: 0x836B…9Ee2

Real usage

Paying agents: 1 in 30 days
Paid calls: 3 in 30 days
Last paid call: 5 days ago

Source: x402 Bazaar settlement data.

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Trust score

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