65trust / 100

Calc Hfa Icos Myeloma

x402 APIFailing, checked 2 h ago

Lyon 2020 HFA-ICOS baseline CV risk before proteasome inhibitors and immunomodulatory drugs for multiple myeloma. Returns risk_level low, medium, high, or very_high plus medium_points and the paper's expert-opinion cardiotoxicity_guide. Age >=75 is High; 65-74 is Medium 1. Caller assigns labs, BMI >30, and high-dose dexamethasone. magent does not examine the patient or read imaging. Not a medical device or treatment order.

POST

https://api.magentlab.com/api/calc/hfa_icos_myeloma

Price: $0.007; per call in USDC
Uptime: 88.9%; last 30 days
Response time: 270 ms; 813 ms slowest 5%
Last check: Failed; 2 h ago, next any minute now

Run a free test call How to call it

Reliability

All checks passedSome failedAll failedNot checked

Latest check failed 2 h ago: Timed out

Status and outage history · Atom feed · Watch with other listings

How to call it

POST https://api.magentlab.com/api/calc/hfa_icos_myeloma

Each call costs $0.007 in USDC on Base, paid with the request over x402.

Run a free test callOne unpaid request, the way an agent sends it. You see the payment challenge it gets back. Nothing is charged.

Example request

From the listing.

POST https://api.magentlab.com/api/calc/hfa_icos_myeloma
content-type: application/json

{
  "items": [
    {
      "age_years": 50,
      "arrhythmia": false,
      "arterial_vascular_disease": false,
      "cardiac_amyloidosis": false,
      "ckd": false,
      "current_or_significant_smoker": false,
      "diabetes": false,
      "elevated_bnp": false,
      "elevated_troponin": false,
      "family_history_thrombophilia": false,
      "heart_failure_or_cardiomyopathy": false,
      "high_dose_dexamethasone": false,
      "hyperlipidemia": false,
      "hypertension": false,
      "left_ventricular_hypertrophy": false,
      "lvef_percent": 60,
      "obesity": false,
      "prior_anthracycline": false,
      "prior_immunomodulatory_drug_cv_toxicity": false,
      "prior_proteasome_inhibitor_cardiotoxicity": false,
      "prior_thoracic_spine_radiotherapy": false,
      "venous_thrombosis": false
    },
    {
      "age_years": 50,
      "arrhythmia": false,
      "arterial_vascular_disease": false,
      "cardiac_amyloidosis": false,
      "ckd": false,
      "current_or_significant_smoker": false,
      "diabetes": false,
      "elevated_bnp": false,
      "elevated_troponin": false,
      "family_history_thrombophilia": false,
      "heart_failure_or_cardiomyopathy": false,
      "high_dose_dexamethasone": false,
      "hyperlipidemia": false,
      "hypertension": false,
      "left_ventricular_hypertrophy": false,
      "lvef_percent": 60,
      "obesity": false,
      "prior_anthracycline": false,
      "prior_immunomodulatory_drug_cv_toxicity": false,
      "prior_proteasome_inhibitor_cardiotoxicity": false,
      "prior_thoracic_spine_radiotherapy": false,
      "venous_thrombosis": false
    }
  ]
}

Parameters

Parameter	Type	Required	Description
`items`	array of object	Yes

Example response

The provider's example. We can't check it without paying. Shortened for display.

Example response, 286 lines

{
  "count": 2,
  "items": [
    {
      "age_years": 50,
      "cardiotoxicity_guide": "<2%",
      "citation": {
        "authors": "Lyon AR, Dent S, Stanway S, et al.",
        "doi": "10.1002/ejhf.1920",
        "id": "lyon-2020",
        "pmid": "32458582",
        "source": "Eur J Heart Fail. 2020;22(11):1945-1960",
        "title": "Baseline cardiovascular risk assessment in cancer patients scheduled to receive cardiotoxic cancer therapies: a position statement and new risk assessment tools from the Cardio-Oncology Study Group of the Heart Failure Association of the European Society of Cardiology in collaboration with the International Cardio-Oncology Society"
      },
      "components": [
        {
          "factor": "heart_failure_or_cardiomyopathy",
          "points": 0,
          "present": false,
          "tier": "very_high"
        },
        {
          "factor": "prior_proteasome_inhibitor_cardiotoxicity",
          "points": 0,
          "present": false,
          "tier": "very_high"
        },
        {
          "factor": "venous_thrombosis",
          "points": 0,
          "present": false,
          "tier": "very_high"
        },
        {
          "factor": "cardiac_amyloidosis",
          "points": 0,
          "present": false,
          "tier": "very_high"
        },
        {
          "factor": "arterial_vascular_disease",
          "points": 0,
          "present": false,
          "tier": "very_high"
        },
        {
          "factor": "prior_immunomodulatory_drug_cv_toxicity",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "elevated_bnp",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "prior_anthracycline",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "arrhythmia",
          "points": 0,
          "present": false,
          "tier": "medium_2"
        },
        {
          "factor": "elevated_troponin",
          "points": 0,
          "present": false,
          "tier": "medium_2"
        },
        {
          "factor": "left_ventricular_hypertrophy",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "hypertension",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "diabetes",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "hyperlipidemia",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "ckd",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "family_history_thrombophilia",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "prior_thoracic_spine_radiotherapy",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "high_dose_dexamethasone",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "current_or_significant_smoker",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "obesity",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "formula": "hfa_icos_myeloma",
      "formula_expression": "very_high if any Very high factor (heart_failure_or_cardiomyopathy, prior_proteasome_inhibitor_cardiotoxicity, venous_thrombosis, cardiac_amyloidosis, arterial_vascular_disease); else high if any High factor (prior_immunomodulatory_drug_cv_toxicity, lvef_percent<50, elevated_bnp, age_years>=75, prior_anthracycline) OR medium_points>=5; else medium if medium_points in 2..4; else low (no factors or one Medium 1). medium_points sums Medium 1 (=1: left_ventricular_hypertrophy, age_years 65-74, hypertension, diabetes, hyperlipidemia, ckd, family_history_thrombophilia, prior_thoracic_spine_radiotherapy, high_dose_dexamethasone, current_or_significant_smoker, obesity) and Medium 2 (=2: lvef_percent 50-54, arrhythmia, elevated_troponin) only. Age and LVEF use the highest matching printed band. Lyon 2020 HFA-ICOS multiple-myeloma therapy table. cardiotoxicity_guide is that paper's expert-opinion guide: low <2%, medium 2-9%, high 10-19%, very high >=20%",
      "lvef_percent": 60,
      "medium_points": 0,
      "risk_level": "low"
    },
    {
      "age_years": 50,
      "cardiotoxicity_guide": "<2%",
      "citation": {
        "authors": "Lyon AR, Dent S, Stanway S, et al.",
        "doi": "10.1002/ejhf.1920",
        "id": "lyon-2020",
        "pmid": "32458582",
        "source": "Eur J Heart Fail. 2020;22(11):1945-1960",
        "title": "Baseline cardiovascular risk assessment in cancer patients scheduled to receive cardiotoxic cancer therapies: a position statement and new risk assessment tools from the Cardio-Oncology Study Group of the Heart Failure Association of the European Society of Cardiology in collaboration with the International Cardio-Oncology Society"
      },
      "components": [
        {
          "factor": "heart_failure_or_cardiomyopathy",
          "points": 0,
          "present": false,
          "tier": "very_high"
        },
        {
          "factor": "prior_proteasome_inhibitor_cardiotoxicity",
          "points": 0,
          "present": false,
          "tier": "very_high"
        },
        {
          "factor": "venous_thrombosis",
          "points": 0,
          "present": false,
          "tier": "very_high"
        },
        {
          "factor": "cardiac_amyloidosis",
          "points": 0,
          "present": false,
          "tier": "very_high"
        },
        {
          "factor": "arterial_vascular_disease",
          "points": 0,
          "present": false,
          "tier": "very_high"
        },
        {
          "factor": "prior_immunomodulatory_drug_cv_toxicity",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "elevated_bnp",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "prior_anthracycline",
          "points": 0,
          "present": false,
          "tier": "high"
        },
        {
          "factor": "arrhythmia",
          "points": 0,
          "present": false,
          "tier": "medium_2"
        },
        {
          "factor": "elevated_troponin",
          "points": 0,
          "present": false,
          "tier": "medium_2"
        },
        {
          "factor": "left_ventricular_hypertrophy",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "hypertension",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "diabetes",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "hyperlipidemia",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "ckd",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "family_history_thrombophilia",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "prior_thoracic_spine_radiotherapy",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "high_dose_dexamethasone",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "current_or_significant_smoker",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        },
        {
          "factor": "obesity",
          "points": 0,
          "present": false,
          "tier": "medium_1"
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "formula": "hfa_icos_myeloma",
      "formula_expression": "very_high if any Very high factor (heart_failure_or_cardiomyopathy, prior_proteasome_inhibitor_cardiotoxicity, venous_thrombosis, cardiac_amyloidosis, arterial_vascular_disease); else high if any High factor (prior_immunomodulatory_drug_cv_toxicity, lvef_percent<50, elevated_bnp, age_years>=75, prior_anthracycline) OR medium_points>=5; else medium if medium_points in 2..4; else low (no factors or one Medium 1). medium_points sums Medium 1 (=1: left_ventricular_hypertrophy, age_years 65-74, hypertension, diabetes, hyperlipidemia, ckd, family_history_thrombophilia, prior_thoracic_spine_radiotherapy, high_dose_dexamethasone, current_or_significant_smoker, obesity) and Medium 2 (=2: lvef_percent 50-54, arrhythmia, elevated_troponin) only. Age and LVEF use the highest matching printed band. Lyon 2020 HFA-ICOS multiple-myeloma therapy table. cardiotoxicity_guide is that paper's expert-opinion guide: low <2%, medium 2-9%, high 10-19%, very high >=20%",
      "lvef_percent": 60,
      "medium_points": 0,
      "risk_level": "low"
    }
  ],
  "path": "/api/calc/hfa_icos_myeloma"
}

Call it from code

The curl command shows the payment challenge. The JavaScript and Python versions pay and call, and never pay more than $0.007.

curl: see the payment challenge

# bash or zsh: see the payment challenge. Nothing is charged.
curl -sS -g -i -X POST 'https://api.magentlab.com/api/calc/hfa_icos_myeloma' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"age_years":50,"arrhythmia":false,"arterial_vascular_disease":false,"cardiac_amyloidosis":false,"ckd":false,"current_or_significant_smoker":false,"diabetes":false,"elevated_bnp":false,"elevated_troponin":false,"family_history_thrombophilia":false,"heart_failure_or_cardiomyopathy":false,"high_dose_dexamethasone":false,"hyperlipidemia":false,"hypertension":false,"left_ventricular_hypertrophy":false,"lvef_percent":60,"obesity":false,"prior_anthracycline":false,"prior_immunomodulatory_drug_cv_toxicity":false,"prior_proteasome_inhibitor_cardiotoxicity":false,"prior_thoracic_spine_radiotherapy":false,"venous_thrombosis":false},{"age_years":50,"arrhythmia":false,"arterial_vascular_disease":false,"cardiac_amyloidosis":false,"ckd":false,"current_or_significant_smoker":false,"diabetes":false,"elevated_bnp":false,"elevated_troponin":false,"family_history_thrombophilia":false,"heart_failure_or_cardiomyopathy":false,"high_dose_dexamethasone":false,"hyperlipidemia":false,"hypertension":false,"left_ventricular_hypertrophy":false,"lvef_percent":60,"obesity":false,"prior_anthracycline":false,"prior_immunomodulatory_drug_cv_toxicity":false,"prior_proteasome_inhibitor_cardiotoxicity":false,"prior_thoracic_spine_radiotherapy":false,"venous_thrombosis":false}]}'

# x402 v2 sends the challenge base64-encoded in the PAYMENT-REQUIRED header (v1 sends it in the body).
# To read the header:
curl -sS -g -o /dev/null -D - -X POST 'https://api.magentlab.com/api/calc/hfa_icos_myeloma' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"age_years":50,"arrhythmia":false,"arterial_vascular_disease":false,"cardiac_amyloidosis":false,"ckd":false,"current_or_significant_smoker":false,"diabetes":false,"elevated_bnp":false,"elevated_troponin":false,"family_history_thrombophilia":false,"heart_failure_or_cardiomyopathy":false,"high_dose_dexamethasone":false,"hyperlipidemia":false,"hypertension":false,"left_ventricular_hypertrophy":false,"lvef_percent":60,"obesity":false,"prior_anthracycline":false,"prior_immunomodulatory_drug_cv_toxicity":false,"prior_proteasome_inhibitor_cardiotoxicity":false,"prior_thoracic_spine_radiotherapy":false,"venous_thrombosis":false},{"age_years":50,"arrhythmia":false,"arterial_vascular_disease":false,"cardiac_amyloidosis":false,"ckd":false,"current_or_significant_smoker":false,"diabetes":false,"elevated_bnp":false,"elevated_troponin":false,"family_history_thrombophilia":false,"heart_failure_or_cardiomyopathy":false,"high_dose_dexamethasone":false,"hyperlipidemia":false,"hypertension":false,"left_ventricular_hypertrophy":false,"lvef_percent":60,"obesity":false,"prior_anthracycline":false,"prior_immunomodulatory_drug_cv_toxicity":false,"prior_proteasome_inhibitor_cardiotoxicity":false,"prior_thoracic_spine_radiotherapy":false,"venous_thrombosis":false}]}' \
  | grep -i '^payment-required:' | cut -d' ' -f2 | tr -d '\r' | base64 --decode

JavaScript: pay and call

// npm i @x402/fetch @x402/evm viem
import { wrapFetchWithPayment, x402Client } from "@x402/fetch";
import { registerExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";

// Pays at most $0.007 per call.
const client = new x402Client().setSpendControls({ maxAmountPerPayment: "$0.007" });
registerExactEvmScheme(client, { signer: privateKeyToAccount(process.env.EVM_PRIVATE_KEY) });
const pay = wrapFetchWithPayment(fetch, client);

// Not sure it's safe to pay? ToolVet checks it first for $0.005. Pay for that from a separate
// client: this one is capped at $0.007 per payment. GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Fapi.magentlab.com%2Fapi%2Fcalc%2Fhfa_icos_myeloma&method=POST
const res = await pay("https://api.magentlab.com/api/calc/hfa_icos_myeloma", {
  method: "POST",
  headers: { "content-type": "application/json" },
  body: JSON.stringify({
    "items": [
      {
        "age_years": 50,
        "arrhythmia": false,
        "arterial_vascular_disease": false,
        "cardiac_amyloidosis": false,
        "ckd": false,
        "current_or_significant_smoker": false,
        "diabetes": false,
        "elevated_bnp": false,
        "elevated_troponin": false,
        "family_history_thrombophilia": false,
        "heart_failure_or_cardiomyopathy": false,
        "high_dose_dexamethasone": false,
        "hyperlipidemia": false,
        "hypertension": false,
        "left_ventricular_hypertrophy": false,
        "lvef_percent": 60,
        "obesity": false,
        "prior_anthracycline": false,
        "prior_immunomodulatory_drug_cv_toxicity": false,
        "prior_proteasome_inhibitor_cardiotoxicity": false,
        "prior_thoracic_spine_radiotherapy": false,
        "venous_thrombosis": false
      },
      {
        "age_years": 50,
        "arrhythmia": false,
        "arterial_vascular_disease": false,
        "cardiac_amyloidosis": false,
        "ckd": false,
        "current_or_significant_smoker": false,
        "diabetes": false,
        "elevated_bnp": false,
        "elevated_troponin": false,
        "family_history_thrombophilia": false,
        "heart_failure_or_cardiomyopathy": false,
        "high_dose_dexamethasone": false,
        "hyperlipidemia": false,
        "hypertension": false,
        "left_ventricular_hypertrophy": false,
        "lvef_percent": 60,
        "obesity": false,
        "prior_anthracycline": false,
        "prior_immunomodulatory_drug_cv_toxicity": false,
        "prior_proteasome_inhibitor_cardiotoxicity": false,
        "prior_thoracic_spine_radiotherapy": false,
        "venous_thrombosis": false
      }
    ]
  }),
});
console.log(res.status, await res.text());

Python: pay and call

# pip install "x402[requests,evm]"
import os
from eth_account import Account
from x402 import x402ClientSync
from x402.http.clients import x402_requests
from x402.mechanisms.evm import EthAccountSigner
from x402.mechanisms.evm.exact.register import register_exact_evm_client

# Pays at most $0.007 per call.
client = x402ClientSync().set_spend_controls({"max_amount_per_payment": "$0.007"})
register_exact_evm_client(client, EthAccountSigner(Account.from_key(os.environ["EVM_PRIVATE_KEY"])))

with x402_requests(client) as session:
    res = session.post(
        "https://api.magentlab.com/api/calc/hfa_icos_myeloma",
        json={
            "items": [
                {
                    "age_years": 50,
                    "arrhythmia": False,
                    "arterial_vascular_disease": False,
                    "cardiac_amyloidosis": False,
                    "ckd": False,
                    "current_or_significant_smoker": False,
                    "diabetes": False,
                    "elevated_bnp": False,
                    "elevated_troponin": False,
                    "family_history_thrombophilia": False,
                    "heart_failure_or_cardiomyopathy": False,
                    "high_dose_dexamethasone": False,
                    "hyperlipidemia": False,
                    "hypertension": False,
                    "left_ventricular_hypertrophy": False,
                    "lvef_percent": 60,
                    "obesity": False,
                    "prior_anthracycline": False,
                    "prior_immunomodulatory_drug_cv_toxicity": False,
                    "prior_proteasome_inhibitor_cardiotoxicity": False,
                    "prior_thoracic_spine_radiotherapy": False,
                    "venous_thrombosis": False,
                },
                {
                    "age_years": 50,
                    "arrhythmia": False,
                    "arterial_vascular_disease": False,
                    "cardiac_amyloidosis": False,
                    "ckd": False,
                    "current_or_significant_smoker": False,
                    "diabetes": False,
                    "elevated_bnp": False,
                    "elevated_troponin": False,
                    "family_history_thrombophilia": False,
                    "heart_failure_or_cardiomyopathy": False,
                    "high_dose_dexamethasone": False,
                    "hyperlipidemia": False,
                    "hypertension": False,
                    "left_ventricular_hypertrophy": False,
                    "lvef_percent": 60,
                    "obesity": False,
                    "prior_anthracycline": False,
                    "prior_immunomodulatory_drug_cv_toxicity": False,
                    "prior_proteasome_inhibitor_cardiotoxicity": False,
                    "prior_thoracic_spine_radiotherapy": False,
                    "venous_thrombosis": False,
                },
            ],
        },
    )
    print(res.status_code, res.text)

Security scan

1 finding

Charges more than its listed price in payment
Listed at $0.005, charges $0.007

Recent checks

When	Result	HTTP	Time	Price
2 h ago	Timed out	-	-	-
8 h ago	Timed out	-	-	-
13 h ago	Timed out	-	-	-
18 h ago	Timed out	-	-	-
22 h ago	Passed	402	184 ms	$0.007

Show 10 older checks

27 h ago	Passed	402	426 ms	$0.007
32 h ago	Passed	402	168 ms	$0.007
37 h ago	Passed	402	339 ms	$0.007
41 h ago	Passed	402	358 ms	$0.007
46 h ago	Passed	402	813 ms	$0.007
2 days ago	Passed	402	289 ms	$0.007
2 days ago	Passed	402	355 ms	$0.007
2 days ago	Passed	402	208 ms	$0.007
3 days ago	Passed	402	151 ms	$0.007
3 days ago	Passed	402	180 ms	$0.007

History

11 Oct 2026	Price changed from $0.005 to $0.007

Trust score 65/ 100

Availability (30-day uptime)		27 / 30
Valid x402 challenge		15 / 15
Response time		10 / 10
Real paying agents (30 days)		3 / 15
Charges what it lists		0 / 10
Security scan		10 / 10
Verified owner		0 / 10

How the score works

Payment terms

Price: $0.007 per call
Listed at: $0.005 (charges more)
Token: USDC
Networks: Base
Pays to: 0x836B…9Ee2

Real usage

Paying agents: 1 in 30 days
Paid calls: 3 in 30 days
Last paid call: 5 days ago

Source: x402 Bazaar settlement data.

Is this your service?

Verify ownership to get the badge and 10 more trust points. Featured placement needs it too.

Verify ownership

Changed something? Check it again now and see what agents get.

Show the score

A badge for your README or docs. It updates with every check and links here.

Trust score

[![ToolVet trust score](https://toolvet.app/badge/calc-hfa-icos-myeloma.svg)](https://toolvet.app/s/calc-hfa-icos-myeloma)