Calc Imwg Myeloma
by magent in Other
IMWG 2014 myeloma requiring therapy (Rajkumar 2014). Met when clonal BMPC ≥10% or biopsy-proven plasmacytoma plus ≥1 MDE: hypercalcemia, renal insufficiency, anemia, osteolytic lesion (CRAB), or BMPC ≥60%, involved:uninvolved FLC ratio ≥100 with involved FLC ≥100 mg/L, or >1 focal MRI lesion ≥5 mm (SLiM). Not a diagnosis. Not smouldering MM, MGUS, POEMS, or amyloid. Not Greipp ISS or R-ISS. magent does not assay calcium, creatinine, hemoglobin, or FLC, and does not read MRI.
https://api.magentlab.com/api/calc/imwg_myeloma- Price
- $0.005
- per call in USDC
- Uptime
- 100%
- last 30 days
- Response time
- 300 ms
- 474 ms slowest 5%
- Last check
- Passed
- 55 min ago, next in 5 h
Reliability
Status and outage history · Atom feed · Watch with other listings
How to call it
GET https://api.magentlab.com/api/calc/imwg_myeloma
Each call costs $0.005 in USDC on Base, paid with the request over x402.
Run a free test callOne unpaid request, the way an agent sends it. You see the payment challenge it gets back. Nothing is charged.
Example request
From the listing.
GET https://api.magentlab.com/api/calc/imwg_myeloma?anemia=false&bmpc_ge_60=false&clonal_bmpc_ge_10_or_plasmacytoma=true&flc_ratio_ge_100=false&hypercalcemia=true&mri_gt_1_focal=false&osteolytic_lesion=false&renal_insufficiency=falseParameters
| Parameter | Type | Required | Description |
|---|---|---|---|
anemia | boolean | Yes | Anemia as assigned by the caller (Rajkumar 2014 CRAB): hemoglobin value >20 g/L below the lower limit of normal or hemoglobin <100 g/L. true or false. magent does not assay hemoglobin. |
bmpc_ge_60 | boolean | Yes | Clonal bone marrow plasma cells ≥60%, as assigned by the caller (Rajkumar 2014 SLiM). true or false. magent does not read a marrow. |
clonal_bmpc_ge_10_or_plasmacytoma | boolean | Yes | Clonal bone marrow plasma cells ≥10% or biopsy-proven bony or extramedullary plasmacytoma, as assigned by the caller (Rajkumar 2014 IMWG entry for myeloma requiring therapy). true or false. When false, myeloma is false even if a myeloma-defining event is true. magent does not read a marrow or biops… |
flc_ratio_ge_100 | boolean | Yes | Involved:uninvolved serum free light-chain ratio ≥100 and involved free light chain ≥100 mg/L, as assigned by the caller as this one flag (Rajkumar 2014 SLiM). true or false. magent does not assay free light chains. |
hypercalcemia | boolean | Yes | Hypercalcemia as assigned by the caller (Rajkumar 2014 CRAB): serum calcium >0.25 mmol/L (>1 mg/dL) above the upper limit of normal or >2.75 mmol/L (>11 mg/dL). true or false. magent does not assay calcium. |
mri_gt_1_focal | boolean | Yes | >1 focal lesion on MRI, each ≥5 mm, as assigned by the caller (Rajkumar 2014 SLiM). true or false. magent does not read MRI. |
osteolytic_lesion | boolean | Yes | One or more osteolytic lesions on skeletal radiography, CT, or PET-CT, as assigned by the caller (Rajkumar 2014 CRAB). If marrow clonal plasma cells are <10%, more than one bone lesion is required to distinguish solitary plasmacytoma; that is the caller’s assignment of this flag. true or false. mag… |
renal_insufficiency | boolean | Yes | Renal insufficiency as assigned by the caller (Rajkumar 2014 CRAB): creatinine clearance <40 mL/min or serum creatinine >177 µmol/L (>2 mg/dL). true or false. magent does not assay creatinine. |
Example response
The provider's example. We can't check it without paying.
Example response, 61 lines
{
"anemia": false,
"any_mde": true,
"bmpc_ge_60": false,
"citation": {
"authors": "Rajkumar SV, Dimopoulos MA, Palumbo A, Blade J, Merlini G, Mateos MV, Kumar S, Hillengass J, Kastritis E, Richardson P, Landgren O, Paiva B, Dispenzieri A, Weiss B, LeLeu X, Zweegman S, Lonial S, Rosinol L, Zamagni E, Jagannath S, Sezer O, Kristinsson SY, Caers J, Usmani SZ, Lahuerta JJ, Johnsen HE, Beksac M, Cavo M, Goldschmidt H, Terpos E, Kyle RA, Anderson KC, Durie BGM, San Miguel JF",
"doi": "10.1016/S1470-2045(14)70442-5",
"id": "rajkumar-2014",
"pmid": "25439696",
"source": "Lancet Oncol. 2014;15(12):e538-e548",
"title": "International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma"
},
"clonal_bmpc_ge_10_or_plasmacytoma": true,
"criteria": [
{
"factor": "clonal_bmpc_ge_10_or_plasmacytoma",
"met": true
},
{
"factor": "hypercalcemia",
"met": true
},
{
"factor": "renal_insufficiency",
"met": false
},
{
"factor": "anemia",
"met": false
},
{
"factor": "osteolytic_lesion",
"met": false
},
{
"factor": "bmpc_ge_60",
"met": false
},
{
"factor": "flc_ratio_ge_100",
"met": false
},
{
"factor": "mri_gt_1_focal",
"met": false
},
{
"factor": "any_mde",
"met": true
}
],
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"flc_ratio_ge_100": false,
"formula": "imwg_myeloma",
"formula_expression": "myeloma iff clonal_bmpc_ge_10_or_plasmacytoma and ≥1 myeloma-defining event (hypercalcemia, renal_insufficiency, anemia, osteolytic_lesion, bmpc_ge_60, flc_ratio_ge_100, or mri_gt_1_focal) (Rajkumar 2014 IMWG definition of multiple myeloma requiring therapy). Not a diagnosis. Not smouldering MM, MGUS, POEMS, or amyloid. Not Greipp ISS. Not R-ISS",
"hypercalcemia": true,
"mri_gt_1_focal": false,
"myeloma": true,
"osteolytic_lesion": false,
"renal_insufficiency": false
}Call it from code
The curl command shows the payment challenge. The JavaScript and Python versions pay and call, and never pay more than $0.005.
curl: see the payment challenge
# bash or zsh: see the payment challenge. Nothing is charged.
curl -sS -g -i 'https://api.magentlab.com/api/calc/imwg_myeloma?anemia=false&bmpc_ge_60=false&clonal_bmpc_ge_10_or_plasmacytoma=true&flc_ratio_ge_100=false&hypercalcemia=true&mri_gt_1_focal=false&osteolytic_lesion=false&renal_insufficiency=false'
# x402 v2 sends the challenge base64-encoded in the PAYMENT-REQUIRED header (v1 sends it in the body).
# To read the header:
curl -sS -g -o /dev/null -D - 'https://api.magentlab.com/api/calc/imwg_myeloma?anemia=false&bmpc_ge_60=false&clonal_bmpc_ge_10_or_plasmacytoma=true&flc_ratio_ge_100=false&hypercalcemia=true&mri_gt_1_focal=false&osteolytic_lesion=false&renal_insufficiency=false' \
| grep -i '^payment-required:' | cut -d' ' -f2 | tr -d '\r' | base64 --decodeJavaScript: pay and call
// npm i @x402/fetch @x402/evm viem
import { wrapFetchWithPayment, x402Client } from "@x402/fetch";
import { registerExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";
// Pays at most $0.005 per call.
const client = new x402Client().setSpendControls({ maxAmountPerPayment: "$0.005" });
registerExactEvmScheme(client, { signer: privateKeyToAccount(process.env.EVM_PRIVATE_KEY) });
const pay = wrapFetchWithPayment(fetch, client);
// Not sure it's safe to pay? ToolVet checks it first for $0.005. Pay for that from a separate
// client: this one is capped at $0.005 per payment. GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Fapi.magentlab.com%2Fapi%2Fcalc%2Fimwg_myeloma
const res = await pay("https://api.magentlab.com/api/calc/imwg_myeloma?anemia=false&bmpc_ge_60=false&clonal_bmpc_ge_10_or_plasmacytoma=true&flc_ratio_ge_100=false&hypercalcemia=true&mri_gt_1_focal=false&osteolytic_lesion=false&renal_insufficiency=false");
console.log(res.status, await res.text());Python: pay and call
# pip install "x402[requests,evm]"
import os
from eth_account import Account
from x402 import x402ClientSync
from x402.http.clients import x402_requests
from x402.mechanisms.evm import EthAccountSigner
from x402.mechanisms.evm.exact.register import register_exact_evm_client
# Pays at most $0.005 per call.
client = x402ClientSync().set_spend_controls({"max_amount_per_payment": "$0.005"})
register_exact_evm_client(client, EthAccountSigner(Account.from_key(os.environ["EVM_PRIVATE_KEY"])))
with x402_requests(client) as session:
res = session.get("https://api.magentlab.com/api/calc/imwg_myeloma?anemia=false&bmpc_ge_60=false&clonal_bmpc_ge_10_or_plasmacytoma=true&flc_ratio_ge_100=false&hypercalcemia=true&mri_gt_1_focal=false&osteolytic_lesion=false&renal_insufficiency=false")
print(res.status_code, res.text)Security scan
No findings
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Recent checks
| When | Result | HTTP | Time | Price |
|---|---|---|---|---|
| 55 min ago | Passed | 402 | 382 ms | $0.005 |
| 12 h ago | Passed | 402 | 474 ms | $0.005 |
| 21 h ago | Passed | 402 | 424 ms | $0.005 |
| 31 h ago | Passed | 402 | 280 ms | $0.005 |
| 42 h ago | Passed | 402 | 331 ms | $0.005 |
Show 6 older checks
| 2 days ago | Passed | 402 | 300 ms | $0.005 |
| 3 days ago | Passed | 402 | 173 ms | $0.005 |
| 3 days ago | Passed | 402 | 300 ms | $0.005 |
| 3 days ago | Passed | 402 | 215 ms | $0.005 |
| 4 days ago | Passed | 402 | 162 ms | $0.005 |
| 4 days ago | Passed | 402 | 140 ms | $0.005 |