ToolVet
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Calc Irae Hepatitis

by magent in Other

x402 APIFailing, checked 7 min ago

ASCO 2018 (Brahmer) immune-related hepatitis grade from caller AST, ALT, and total bilirubin as folds of laboratory ULN (mg/dL only). Lab grade is the max of transaminase and bilirubin Table 2.2 bands; decompensated liver upgrades to grade 4; symptomatic compensated liver dysfunction upgrades to grade 3. ICI action: continue (0-1), hold (2), or permanently discontinue (3-4). Not a medical device, not a diagnosis, not DILI/RUCAM, not R factor, not a steroid dose; magent does not assay enzymes.

POST
https://api.magentlab.com/api/calc/irae_hepatitis
Price
$0.007
per call in USDC
Uptime
94.1%
last 30 days
Response time
163 ms
401 ms slowest 5%
Last check
Failed
7 min ago, next in 9 min

Run a free test callHow to call it

Reliability

All checks passedSome failedAll failedNot checked

Latest check failed 7 min ago: Timed out

Status and outage history · Atom feed · Watch with other listings

How to call it

POST https://api.magentlab.com/api/calc/irae_hepatitis

Each call costs $0.007 in USDC on Base, paid with the request over x402.

Run a free test callOne unpaid request, the way an agent sends it. You see the payment challenge it gets back. Nothing is charged.

Example request

From the listing.

POST https://api.magentlab.com/api/calc/irae_hepatitis
content-type: application/json

{
  "items": [
    {
      "alt_u_l": 50,
      "alt_uln_u_l": 40,
      "ast_u_l": 80,
      "ast_uln_u_l": 40,
      "bilirubin_mg_dl": 1,
      "bilirubin_uln_mg_dl": 1,
      "decompensated_liver": false,
      "symptomatic_liver_dysfunction": false
    },
    {
      "alt_u_l": 50,
      "alt_uln_u_l": 40,
      "ast_u_l": 80,
      "ast_uln_u_l": 40,
      "bilirubin_mg_dl": 1,
      "bilirubin_uln_mg_dl": 1,
      "decompensated_liver": false,
      "symptomatic_liver_dysfunction": false
    }
  ]
}

Parameters

ParameterTypeRequiredDescription
itemsarray of objectYes

Example response

The provider's example. We can't check it without paying.

Example response, 76 lines
{
  "count": 2,
  "items": [
    {
      "alt_u_l": 50,
      "alt_uln_u_l": 40,
      "ast_u_l": 80,
      "ast_uln_u_l": 40,
      "bilirubin_mg_dl": 1,
      "bilirubin_ratio": 1,
      "bilirubin_uln_mg_dl": 1,
      "citation": {
        "authors": "Brahmer JR, Lacchetti C, Schneider BJ, Atkins MB, Brassil KJ, Caterino JM, Chau I, Ernstoff MS, Gardner JM, Ginex P, Hallmeyer S, Holter Chakrabarty J, Leighl NB, Mammen JS, McDermott DF, Naing A, Nastoupil LJ, Phillips T, Porter LD, Puzanov I, Reichner CA, Santomasso BD, Seigel C, Spira A, Suarez-Almazor ME, Wang Y, Weber JS, Wolchok JD, Thompson JA",
        "doi": "10.1200/JCO.2017.77.6385",
        "id": "brahmer-2018",
        "pmid": "29442540",
        "source": "J Clin Oncol. 2018;36(17):1714-1768",
        "title": "Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline"
      },
      "criteria": [
        {
          "factor": "decompensated_liver",
          "met": false
        },
        {
          "factor": "symptomatic_liver_dysfunction",
          "met": false
        }
      ],
      "decompensated_liver": false,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "formula": "irae_hepatitis",
      "formula_expression": "lab_grade = max(transaminase_grade(max(AST/AST_ULN, ALT/ALT_ULN)), bilirubin_grade(TBili/TBili_ULN)); first-match: decompensated_liver -> max(lab_grade, 4); else symptomatic_liver_dysfunction -> max(lab_grade, 3); else lab_grade. Transaminase: <1x -> 0, ULN-3x -> 1, >3-5x -> 2, >5-20x -> 3, >20x -> 4. Bilirubin: <1x -> 0, ULN-1.5x -> 1, >1.5-3x -> 2, >3-10x -> 3, >10x -> 4 (Brahmer 2018 Table 2.2). icpi_action: 0-1 continue, 2 hold, 3-4 permanently_discontinue. mg/dL bilirubin only. Not DILI/RUCAM. Not R factor. magent does not assay enzymes. Not a diagnosis. Not a steroid dose",
      "grade": 1,
      "icpi_action": "continue",
      "symptomatic_liver_dysfunction": false,
      "transaminase_ratio": 2
    },
    {
      "alt_u_l": 50,
      "alt_uln_u_l": 40,
      "ast_u_l": 80,
      "ast_uln_u_l": 40,
      "bilirubin_mg_dl": 1,
      "bilirubin_ratio": 1,
      "bilirubin_uln_mg_dl": 1,
      "citation": {
        "authors": "Brahmer JR, Lacchetti C, Schneider BJ, Atkins MB, Brassil KJ, Caterino JM, Chau I, Ernstoff MS, Gardner JM, Ginex P, Hallmeyer S, Holter Chakrabarty J, Leighl NB, Mammen JS, McDermott DF, Naing A, Nastoupil LJ, Phillips T, Porter LD, Puzanov I, Reichner CA, Santomasso BD, Seigel C, Spira A, Suarez-Almazor ME, Wang Y, Weber JS, Wolchok JD, Thompson JA",
        "doi": "10.1200/JCO.2017.77.6385",
        "id": "brahmer-2018",
        "pmid": "29442540",
        "source": "J Clin Oncol. 2018;36(17):1714-1768",
        "title": "Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline"
      },
      "criteria": [
        {
          "factor": "decompensated_liver",
          "met": false
        },
        {
          "factor": "symptomatic_liver_dysfunction",
          "met": false
        }
      ],
      "decompensated_liver": false,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "formula": "irae_hepatitis",
      "formula_expression": "lab_grade = max(transaminase_grade(max(AST/AST_ULN, ALT/ALT_ULN)), bilirubin_grade(TBili/TBili_ULN)); first-match: decompensated_liver -> max(lab_grade, 4); else symptomatic_liver_dysfunction -> max(lab_grade, 3); else lab_grade. Transaminase: <1x -> 0, ULN-3x -> 1, >3-5x -> 2, >5-20x -> 3, >20x -> 4. Bilirubin: <1x -> 0, ULN-1.5x -> 1, >1.5-3x -> 2, >3-10x -> 3, >10x -> 4 (Brahmer 2018 Table 2.2). icpi_action: 0-1 continue, 2 hold, 3-4 permanently_discontinue. mg/dL bilirubin only. Not DILI/RUCAM. Not R factor. magent does not assay enzymes. Not a diagnosis. Not a steroid dose",
      "grade": 1,
      "icpi_action": "continue",
      "symptomatic_liver_dysfunction": false,
      "transaminase_ratio": 2
    }
  ],
  "path": "/api/calc/irae_hepatitis"
}

Call it from code

The curl command shows the payment challenge. The JavaScript and Python versions pay and call, and never pay more than $0.007.

curl: see the payment challenge
# bash or zsh: see the payment challenge. Nothing is charged.
curl -sS -g -i -X POST 'https://api.magentlab.com/api/calc/irae_hepatitis' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"alt_u_l":50,"alt_uln_u_l":40,"ast_u_l":80,"ast_uln_u_l":40,"bilirubin_mg_dl":1,"bilirubin_uln_mg_dl":1,"decompensated_liver":false,"symptomatic_liver_dysfunction":false},{"alt_u_l":50,"alt_uln_u_l":40,"ast_u_l":80,"ast_uln_u_l":40,"bilirubin_mg_dl":1,"bilirubin_uln_mg_dl":1,"decompensated_liver":false,"symptomatic_liver_dysfunction":false}]}'

# x402 v2 sends the challenge base64-encoded in the PAYMENT-REQUIRED header (v1 sends it in the body).
# To read the header:
curl -sS -g -o /dev/null -D - -X POST 'https://api.magentlab.com/api/calc/irae_hepatitis' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"alt_u_l":50,"alt_uln_u_l":40,"ast_u_l":80,"ast_uln_u_l":40,"bilirubin_mg_dl":1,"bilirubin_uln_mg_dl":1,"decompensated_liver":false,"symptomatic_liver_dysfunction":false},{"alt_u_l":50,"alt_uln_u_l":40,"ast_u_l":80,"ast_uln_u_l":40,"bilirubin_mg_dl":1,"bilirubin_uln_mg_dl":1,"decompensated_liver":false,"symptomatic_liver_dysfunction":false}]}' \
  | grep -i '^payment-required:' | cut -d' ' -f2 | tr -d '\r' | base64 --decode
JavaScript: pay and call
// npm i @x402/fetch @x402/evm viem
import { wrapFetchWithPayment, x402Client } from "@x402/fetch";
import { registerExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";

// Pays at most $0.007 per call.
const client = new x402Client().setSpendControls({ maxAmountPerPayment: "$0.007" });
registerExactEvmScheme(client, { signer: privateKeyToAccount(process.env.EVM_PRIVATE_KEY) });
const pay = wrapFetchWithPayment(fetch, client);

// Not sure it's safe to pay? ToolVet checks it first for $0.005. Pay for that from a separate
// client: this one is capped at $0.007 per payment. GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Fapi.magentlab.com%2Fapi%2Fcalc%2Firae_hepatitis&method=POST
const res = await pay("https://api.magentlab.com/api/calc/irae_hepatitis", {
  method: "POST",
  headers: { "content-type": "application/json" },
  body: JSON.stringify({
    "items": [
      {
        "alt_u_l": 50,
        "alt_uln_u_l": 40,
        "ast_u_l": 80,
        "ast_uln_u_l": 40,
        "bilirubin_mg_dl": 1,
        "bilirubin_uln_mg_dl": 1,
        "decompensated_liver": false,
        "symptomatic_liver_dysfunction": false
      },
      {
        "alt_u_l": 50,
        "alt_uln_u_l": 40,
        "ast_u_l": 80,
        "ast_uln_u_l": 40,
        "bilirubin_mg_dl": 1,
        "bilirubin_uln_mg_dl": 1,
        "decompensated_liver": false,
        "symptomatic_liver_dysfunction": false
      }
    ]
  }),
});
console.log(res.status, await res.text());
Python: pay and call
# pip install "x402[requests,evm]"
import os
from eth_account import Account
from x402 import x402ClientSync
from x402.http.clients import x402_requests
from x402.mechanisms.evm import EthAccountSigner
from x402.mechanisms.evm.exact.register import register_exact_evm_client

# Pays at most $0.007 per call.
client = x402ClientSync().set_spend_controls({"max_amount_per_payment": "$0.007"})
register_exact_evm_client(client, EthAccountSigner(Account.from_key(os.environ["EVM_PRIVATE_KEY"])))

with x402_requests(client) as session:
    res = session.post(
        "https://api.magentlab.com/api/calc/irae_hepatitis",
        json={
            "items": [
                {
                    "alt_u_l": 50,
                    "alt_uln_u_l": 40,
                    "ast_u_l": 80,
                    "ast_uln_u_l": 40,
                    "bilirubin_mg_dl": 1,
                    "bilirubin_uln_mg_dl": 1,
                    "decompensated_liver": False,
                    "symptomatic_liver_dysfunction": False,
                },
                {
                    "alt_u_l": 50,
                    "alt_uln_u_l": 40,
                    "ast_u_l": 80,
                    "ast_uln_u_l": 40,
                    "bilirubin_mg_dl": 1,
                    "bilirubin_uln_mg_dl": 1,
                    "decompensated_liver": False,
                    "symptomatic_liver_dysfunction": False,
                },
            ],
        },
    )
    print(res.status_code, res.text)

Security scan

1 finding

  • Charges more than its listed price in payment
    Listed at $0.005, charges $0.007

Recent checks

WhenResultHTTPTimePrice
7 min agoTimed out---
5 h agoTimed out---
10 h agoPassed402145 ms$0.007
14 h agoPassed402177 ms$0.007
19 h agoPassed402380 ms$0.007
Show 10 older checks
24 h agoPassed402150 ms$0.007
28 h agoPassed402401 ms$0.007
33 h agoPassed402143 ms$0.007
37 h agoPassed402235 ms$0.007
41 h agoPassed402167 ms$0.007
45 h agoPassed402218 ms$0.007
2 days agoPassed402261 ms$0.007
2 days agoPassed402163 ms$0.007
2 days agoPassed402156 ms$0.007
3 days agoPassed402155 ms$0.007

History

11 Oct 2026Price changed from $0.005 to $0.007