Calc Irae Nephritis

{
  "count": 2,
  "items": [
    {
      "baseline_creatinine_mg_dl": 1,
      "citation": {
        "authors": "Brahmer JR, Lacchetti C, Schneider BJ, Atkins MB, Brassil KJ, Caterino JM, Chau I, Ernstoff MS, Gardner JM, Ginex P, Hallmeyer S, Holter Chakrabarty J, Leighl NB, Mammen JS, McDermott DF, Naing A, Nastoupil LJ, Phillips T, Porter LD, Puzanov I, Reichner CA, Santomasso BD, Seigel C, Spira A, Suarez-Almazor ME, Wang Y, Weber JS, Wolchok JD, Thompson JA",
        "doi": "10.1200/JCO.2017.77.6385",
        "id": "brahmer-2018",
        "pmid": "29442540",
        "source": "J Clin Oncol. 2018;36(17):1714-1768",
        "title": "Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline"
      },
      "creatinine_mg_dl": 1.6,
      "criteria": [
        {
          "factor": "dialysis_indicated",
          "met": false
        },
        {
          "factor": "life_threatening",
          "met": false
        },
        {
          "factor": "fold_gt_3",
          "met": false,
          "value": 1.6
        },
        {
          "factor": "creatinine_ge_4",
          "met": false,
          "value": 1.6
        },
        {
          "factor": "hospitalization_indicated",
          "met": false
        },
        {
          "factor": "fold_gt_2",
          "met": false,
          "value": 1.6
        },
        {
          "factor": "fold_ge_1_5",
          "met": true,
          "value": 1.6
        },
        {
          "factor": "delta_ge_0_3",
          "met": true,
          "value": 0.6
        }
      ],
      "delta": 0.6,
      "dialysis_indicated": false,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "fold": 1.6,
      "formula": "irae_nephritis",
      "formula_expression": "irae_nephritis first-match worst-wins (Brahmer 2018 Table 6.1): fold = creatinine_mg_dl / baseline_creatinine_mg_dl; delta = creatinine_mg_dl - baseline_creatinine_mg_dl. Grade 4 if dialysis_indicated or life_threatening; else grade 3 if fold > 3 or creatinine_mg_dl >= 4.0 or hospitalization_indicated; else grade 2 if fold > 2; else grade 1 if fold >= 1.5 or delta >= 0.3; else grade 0. icpi_action: 0 continue, 1 consider_hold, 2 hold, 3-4 permanently_discontinue. mg/dL only. Not KDIGO/AKIN. magent does not assay creatinine. Not a diagnosis. Not a steroid dose",
      "grade": 1,
      "hospitalization_indicated": false,
      "icpi_action": "consider_hold",
      "life_threatening": false
    },
    {
      "baseline_creatinine_mg_dl": 1,
      "citation": {
        "authors": "Brahmer JR, Lacchetti C, Schneider BJ, Atkins MB, Brassil KJ, Caterino JM, Chau I, Ernstoff MS, Gardner JM, Ginex P, Hallmeyer S, Holter Chakrabarty J, Leighl NB, Mammen JS, McDermott DF, Naing A, Nastoupil LJ, Phillips T, Porter LD, Puzanov I, Reichner CA, Santomasso BD, Seigel C, Spira A, Suarez-Almazor ME, Wang Y, Weber JS, Wolchok JD, Thompson JA",
        "doi": "10.1200/JCO.2017.77.6385",
        "id": "brahmer-2018",
        "pmid": "29442540",
        "source": "J Clin Oncol. 2018;36(17):1714-1768",
        "title": "Management of Immune-Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitor Therapy: American Society of Clinical Oncology Clinical Practice Guideline"
      },
      "creatinine_mg_dl": 1.6,
      "criteria": [
        {
          "factor": "dialysis_indicated",
          "met": false
        },
        {
          "factor": "life_threatening",
          "met": false
        },
        {
          "factor": "fold_gt_3",
          "met": false,
          "value": 1.6
        },
        {
          "factor": "creatinine_ge_4",
          "met": false,
          "value": 1.6
        },
        {
          "factor": "hospitalization_indicated",
          "met": false
        },
        {
          "factor": "fold_gt_2",
          "met": false,
          "value": 1.6
        },
        {
          "factor": "fold_ge_1_5",
          "met": true,
          "value": 1.6
        },
        {
          "factor": "delta_ge_0_3",
          "met": true,
          "value": 0.6
        }
      ],
      "delta": 0.6,
      "dialysis_indicated": false,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "fold": 1.6,
      "formula": "irae_nephritis",
      "formula_expression": "irae_nephritis first-match worst-wins (Brahmer 2018 Table 6.1): fold = creatinine_mg_dl / baseline_creatinine_mg_dl; delta = creatinine_mg_dl - baseline_creatinine_mg_dl. Grade 4 if dialysis_indicated or life_threatening; else grade 3 if fold > 3 or creatinine_mg_dl >= 4.0 or hospitalization_indicated; else grade 2 if fold > 2; else grade 1 if fold >= 1.5 or delta >= 0.3; else grade 0. icpi_action: 0 continue, 1 consider_hold, 2 hold, 3-4 permanently_discontinue. mg/dL only. Not KDIGO/AKIN. magent does not assay creatinine. Not a diagnosis. Not a steroid dose",
      "grade": 1,
      "hospitalization_indicated": false,
      "icpi_action": "consider_hold",
      "life_threatening": false
    }
  ],
  "path": "/api/calc/irae_nephritis"
}

# bash or zsh: see the payment challenge. Nothing is charged.
curl -sS -g -i -X POST 'https://api.magentlab.com/api/calc/irae_nephritis' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"baseline_creatinine_mg_dl":1,"creatinine_mg_dl":1.6,"dialysis_indicated":false,"hospitalization_indicated":false,"life_threatening":false},{"baseline_creatinine_mg_dl":1,"creatinine_mg_dl":1.6,"dialysis_indicated":false,"hospitalization_indicated":false,"life_threatening":false}]}'

# x402 v2 sends the challenge base64-encoded in the PAYMENT-REQUIRED header (v1 sends it in the body).
# To read the header:
curl -sS -g -o /dev/null -D - -X POST 'https://api.magentlab.com/api/calc/irae_nephritis' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"baseline_creatinine_mg_dl":1,"creatinine_mg_dl":1.6,"dialysis_indicated":false,"hospitalization_indicated":false,"life_threatening":false},{"baseline_creatinine_mg_dl":1,"creatinine_mg_dl":1.6,"dialysis_indicated":false,"hospitalization_indicated":false,"life_threatening":false}]}' \
  | grep -i '^payment-required:' | cut -d' ' -f2 | tr -d '\r' | base64 --decode

// npm i @x402/fetch @x402/evm viem
import { wrapFetchWithPayment, x402Client } from "@x402/fetch";
import { registerExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";

// Pays at most $0.007 per call.
const client = new x402Client().setSpendControls({ maxAmountPerPayment: "$0.007" });
registerExactEvmScheme(client, { signer: privateKeyToAccount(process.env.EVM_PRIVATE_KEY) });
const pay = wrapFetchWithPayment(fetch, client);

// Not sure it's safe to pay? ToolVet checks it first for $0.005. Pay for that from a separate
// client: this one is capped at $0.007 per payment. GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Fapi.magentlab.com%2Fapi%2Fcalc%2Firae_nephritis&method=POST
const res = await pay("https://api.magentlab.com/api/calc/irae_nephritis", {
  method: "POST",
  headers: { "content-type": "application/json" },
  body: JSON.stringify({
    "items": [
      {
        "baseline_creatinine_mg_dl": 1,
        "creatinine_mg_dl": 1.6,
        "dialysis_indicated": false,
        "hospitalization_indicated": false,
        "life_threatening": false
      },
      {
        "baseline_creatinine_mg_dl": 1,
        "creatinine_mg_dl": 1.6,
        "dialysis_indicated": false,
        "hospitalization_indicated": false,
        "life_threatening": false
      }
    ]
  }),
});
console.log(res.status, await res.text());

# pip install "x402[requests,evm]"
import os
from eth_account import Account
from x402 import x402ClientSync
from x402.http.clients import x402_requests
from x402.mechanisms.evm import EthAccountSigner
from x402.mechanisms.evm.exact.register import register_exact_evm_client

# Pays at most $0.007 per call.
client = x402ClientSync().set_spend_controls({"max_amount_per_payment": "$0.007"})
register_exact_evm_client(client, EthAccountSigner(Account.from_key(os.environ["EVM_PRIVATE_KEY"])))

with x402_requests(client) as session:
    res = session.post(
        "https://api.magentlab.com/api/calc/irae_nephritis",
        json={
            "items": [
                {
                    "baseline_creatinine_mg_dl": 1,
                    "creatinine_mg_dl": 1.6,
                    "dialysis_indicated": False,
                    "hospitalization_indicated": False,
                    "life_threatening": False,
                },
                {
                    "baseline_creatinine_mg_dl": 1,
                    "creatinine_mg_dl": 1.6,
                    "dialysis_indicated": False,
                    "hospitalization_indicated": False,
                    "life_threatening": False,
                },
            ],
        },
    )
    print(res.status_code, res.text)