Calc Leiden Arthritis

{
  "count": 2,
  "items": [
    {
      "citation": {
        "authors": "van der Helm-van Mil AH, le Cessie S, van Dongen H, Breedveld FC, Toes RE, Huizinga TW",
        "doi": "10.1002/art.22380",
        "id": "van-der-helm-van-mil-2007",
        "pmid": "17265478",
        "source": "Arthritis Rheum. 2007;56(2):433-440",
        "title": "A prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis: how to guide individual treatment decisions"
      },
      "components": [
        {
          "factor": "age",
          "points": 0.96,
          "present": true,
          "value": 48
        },
        {
          "factor": "female",
          "points": 1,
          "present": true,
          "value": "female"
        },
        {
          "factor": "small_joints_hands_feet",
          "points": 0.5,
          "present": true
        },
        {
          "factor": "symmetric",
          "points": 0.5,
          "present": true
        },
        {
          "factor": "upper_and_lower_extremities",
          "points": 0,
          "present": false
        },
        {
          "factor": "upper_extremities",
          "points": 1,
          "present": true
        },
        {
          "factor": "morning_stiffness_vas_mm",
          "points": 1,
          "present": true,
          "value": 50
        },
        {
          "factor": "tender_joint_count",
          "points": 0.5,
          "present": true,
          "value": 8
        },
        {
          "factor": "swollen_joint_count",
          "points": 0.5,
          "present": true,
          "value": 8
        },
        {
          "factor": "crp_mg_l",
          "points": 1.5,
          "present": true,
          "value": 60
        },
        {
          "factor": "rheumatoid_factor_positive",
          "points": 0,
          "present": false
        },
        {
          "factor": "anti_ccp_positive",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "formula": "leiden_arthritis",
      "formula_expression": "Leiden UA score (van der Helm-van Mil 2007 Figure 1 / Table 2) = age_years*0.02 + female 1 + small_joints_hands_feet 0.5 + symmetric 0.5 + (upper_and_lower_extremities 1.5 else upper_extremities 1) + morning_stiffness_vas_mm (0–25 → 0; 26–90 → 1; >90 → 2) + tender_joint_count (<4 → 0; 4–10 → 0.5; ≥11 → 1) + swollen_joint_count (<4 → 0; 4–10 → 0.5; ≥11 → 1) + crp_mg_l (0–4 → 0; 5–50 → 0.5; ≥51 → 1.5) + rheumatoid_factor_positive 1 + anti_ccp_positive 2; round to nearest 0.0 or 0.5; ≤6 low, >6 and <8 indeterminate, ≥8 high; max 14; not a diagnosis of RA",
      "leiden_band": "indeterminate",
      "max_score": 14,
      "score": 7.5
    },
    {
      "citation": {
        "authors": "van der Helm-van Mil AH, le Cessie S, van Dongen H, Breedveld FC, Toes RE, Huizinga TW",
        "doi": "10.1002/art.22380",
        "id": "van-der-helm-van-mil-2007",
        "pmid": "17265478",
        "source": "Arthritis Rheum. 2007;56(2):433-440",
        "title": "A prediction rule for disease outcome in patients with recent-onset undifferentiated arthritis: how to guide individual treatment decisions"
      },
      "components": [
        {
          "factor": "age",
          "points": 0.96,
          "present": true,
          "value": 48
        },
        {
          "factor": "female",
          "points": 1,
          "present": true,
          "value": "female"
        },
        {
          "factor": "small_joints_hands_feet",
          "points": 0.5,
          "present": true
        },
        {
          "factor": "symmetric",
          "points": 0.5,
          "present": true
        },
        {
          "factor": "upper_and_lower_extremities",
          "points": 0,
          "present": false
        },
        {
          "factor": "upper_extremities",
          "points": 1,
          "present": true
        },
        {
          "factor": "morning_stiffness_vas_mm",
          "points": 1,
          "present": true,
          "value": 50
        },
        {
          "factor": "tender_joint_count",
          "points": 0.5,
          "present": true,
          "value": 8
        },
        {
          "factor": "swollen_joint_count",
          "points": 0.5,
          "present": true,
          "value": 8
        },
        {
          "factor": "crp_mg_l",
          "points": 1.5,
          "present": true,
          "value": 60
        },
        {
          "factor": "rheumatoid_factor_positive",
          "points": 0,
          "present": false
        },
        {
          "factor": "anti_ccp_positive",
          "points": 0,
          "present": false
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "formula": "leiden_arthritis",
      "formula_expression": "Leiden UA score (van der Helm-van Mil 2007 Figure 1 / Table 2) = age_years*0.02 + female 1 + small_joints_hands_feet 0.5 + symmetric 0.5 + (upper_and_lower_extremities 1.5 else upper_extremities 1) + morning_stiffness_vas_mm (0–25 → 0; 26–90 → 1; >90 → 2) + tender_joint_count (<4 → 0; 4–10 → 0.5; ≥11 → 1) + swollen_joint_count (<4 → 0; 4–10 → 0.5; ≥11 → 1) + crp_mg_l (0–4 → 0; 5–50 → 0.5; ≥51 → 1.5) + rheumatoid_factor_positive 1 + anti_ccp_positive 2; round to nearest 0.0 or 0.5; ≤6 low, >6 and <8 indeterminate, ≥8 high; max 14; not a diagnosis of RA",
      "leiden_band": "indeterminate",
      "max_score": 14,
      "score": 7.5
    }
  ],
  "path": "/api/calc/leiden_arthritis"
}

# bash or zsh: see the payment challenge. Nothing is charged.
curl -sS -g -i -X POST 'https://api.magentlab.com/api/calc/leiden_arthritis' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"age":48,"anti_ccp_positive":false,"crp_mg_l":60,"morning_stiffness_vas_mm":50,"rheumatoid_factor_positive":false,"sex":"female","small_joints_hands_feet":true,"swollen_joint_count":8,"symmetric":true,"tender_joint_count":8,"upper_and_lower_extremities":false,"upper_extremities":true},{"age":48,"anti_ccp_positive":false,"crp_mg_l":60,"morning_stiffness_vas_mm":50,"rheumatoid_factor_positive":false,"sex":"female","small_joints_hands_feet":true,"swollen_joint_count":8,"symmetric":true,"tender_joint_count":8,"upper_and_lower_extremities":false,"upper_extremities":true}]}'

# x402 v2 sends the challenge base64-encoded in the PAYMENT-REQUIRED header (v1 sends it in the body).
# To read the header:
curl -sS -g -o /dev/null -D - -X POST 'https://api.magentlab.com/api/calc/leiden_arthritis' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"age":48,"anti_ccp_positive":false,"crp_mg_l":60,"morning_stiffness_vas_mm":50,"rheumatoid_factor_positive":false,"sex":"female","small_joints_hands_feet":true,"swollen_joint_count":8,"symmetric":true,"tender_joint_count":8,"upper_and_lower_extremities":false,"upper_extremities":true},{"age":48,"anti_ccp_positive":false,"crp_mg_l":60,"morning_stiffness_vas_mm":50,"rheumatoid_factor_positive":false,"sex":"female","small_joints_hands_feet":true,"swollen_joint_count":8,"symmetric":true,"tender_joint_count":8,"upper_and_lower_extremities":false,"upper_extremities":true}]}' \
  | grep -i '^payment-required:' | cut -d' ' -f2 | tr -d '\r' | base64 --decode

// npm i @x402/fetch @x402/evm viem
import { wrapFetchWithPayment, x402Client } from "@x402/fetch";
import { registerExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";

// Pays at most $0.007 per call.
const client = new x402Client().setSpendControls({ maxAmountPerPayment: "$0.007" });
registerExactEvmScheme(client, { signer: privateKeyToAccount(process.env.EVM_PRIVATE_KEY) });
const pay = wrapFetchWithPayment(fetch, client);

// Not sure it's safe to pay? ToolVet checks it first for $0.005. Pay for that from a separate
// client: this one is capped at $0.007 per payment. GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Fapi.magentlab.com%2Fapi%2Fcalc%2Fleiden_arthritis&method=POST
const res = await pay("https://api.magentlab.com/api/calc/leiden_arthritis", {
  method: "POST",
  headers: { "content-type": "application/json" },
  body: JSON.stringify({
    "items": [
      {
        "age": 48,
        "anti_ccp_positive": false,
        "crp_mg_l": 60,
        "morning_stiffness_vas_mm": 50,
        "rheumatoid_factor_positive": false,
        "sex": "female",
        "small_joints_hands_feet": true,
        "swollen_joint_count": 8,
        "symmetric": true,
        "tender_joint_count": 8,
        "upper_and_lower_extremities": false,
        "upper_extremities": true
      },
      {
        "age": 48,
        "anti_ccp_positive": false,
        "crp_mg_l": 60,
        "morning_stiffness_vas_mm": 50,
        "rheumatoid_factor_positive": false,
        "sex": "female",
        "small_joints_hands_feet": true,
        "swollen_joint_count": 8,
        "symmetric": true,
        "tender_joint_count": 8,
        "upper_and_lower_extremities": false,
        "upper_extremities": true
      }
    ]
  }),
});
console.log(res.status, await res.text());

# pip install "x402[requests,evm]"
import os
from eth_account import Account
from x402 import x402ClientSync
from x402.http.clients import x402_requests
from x402.mechanisms.evm import EthAccountSigner
from x402.mechanisms.evm.exact.register import register_exact_evm_client

# Pays at most $0.007 per call.
client = x402ClientSync().set_spend_controls({"max_amount_per_payment": "$0.007"})
register_exact_evm_client(client, EthAccountSigner(Account.from_key(os.environ["EVM_PRIVATE_KEY"])))

with x402_requests(client) as session:
    res = session.post(
        "https://api.magentlab.com/api/calc/leiden_arthritis",
        json={
            "items": [
                {
                    "age": 48,
                    "anti_ccp_positive": False,
                    "crp_mg_l": 60,
                    "morning_stiffness_vas_mm": 50,
                    "rheumatoid_factor_positive": False,
                    "sex": "female",
                    "small_joints_hands_feet": True,
                    "swollen_joint_count": 8,
                    "symmetric": True,
                    "tender_joint_count": 8,
                    "upper_and_lower_extremities": False,
                    "upper_extremities": True,
                },
                {
                    "age": 48,
                    "anti_ccp_positive": False,
                    "crp_mg_l": 60,
                    "morning_stiffness_vas_mm": 50,
                    "rheumatoid_factor_positive": False,
                    "sex": "female",
                    "small_joints_hands_feet": True,
                    "swollen_joint_count": 8,
                    "symmetric": True,
                    "tender_joint_count": 8,
                    "upper_and_lower_extremities": False,
                    "upper_extremities": True,
                },
            ],
        },
    )
    print(res.status_code, res.text)