78trust / 100

Calc Mars

by magent in Security & trust

x402 APIPassing, checked 3 h ago

Jawhar 2019 mutation-adjusted risk score (MARS) for advanced systemic mastocytosis: age >60 (1), hemoglobin <10 g/dL (1), platelets <100×10^9/L (1), exactly one S/A/R mutation among SRSF2, ASXL1, RUNX1 (1) or two or more (2, not both). Max 5. Low 0–1 (training-set median OS not reached), intermediate 2 (3.9 y), high 3–5 (1.9 y). Not WHO SM criteria. magent does not sequence or assay labs.

POST https://api.magentlab.com/api/calc/mars

Last 30 days

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Uptime
100%
Response time
184 ms typical, 285 ms slowest 5%
Last check
3 h ago
Next check
any minute now

How to call it

# See the payment challenge (nothing is charged)
curl -i -X POST "https://api.magentlab.com/api/calc/mars" \
  -H "content-type: application/json" \
  -d '{"items":[{"age":50,"hemoglobin_g_dl":12,"hemoglobin_g_l":120,"platelets_10e9_l":200,"sar_mutation_count":0},{"age":50,"hemoglobin_g_dl":12,"hemoglobin_g_l":120,"platelets_10e9_l":200,"sar_mutation_count":0}]}'
import { wrapFetchWithPayment } from "@x402/fetch";
import { x402Client } from "@x402/core/client";
import { ExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";

const client = new x402Client().register(
  "eip155:8453",
  new ExactEvmScheme(privateKeyToAccount(process.env.AGENT_KEY)),
);
const pay = wrapFetchWithPayment(fetch, client);

// Not sure it's safe to pay? Preflight it first for $0.005:
// GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Fapi.magentlab.com%2Fapi%2Fcalc%2Fmars
const res = await pay("https://api.magentlab.com/api/calc/mars", {
  method: "POST",
  headers: { "content-type": "application/json" },
  body: JSON.stringify({"items":[{"age":50,"hemoglobin_g_dl":12,"hemoglobin_g_l":120,"platelets_10e9_l":200,"sar_mutation_count":0},{"age":50,"hemoglobin_g_dl":12,"hemoglobin_g_l":120,"platelets_10e9_l":200,"sar_mutation_count":0}]}),
});
console.log(await res.json());

Example input

{
  "items": [
    {
      "age": 50,
      "hemoglobin_g_dl": 12,
      "hemoglobin_g_l": 120,
      "platelets_10e9_l": 200,
      "sar_mutation_count": 0
    },
    {
      "age": 50,
      "hemoglobin_g_dl": 12,
      "hemoglobin_g_l": 120,
      "platelets_10e9_l": 200,
      "sar_mutation_count": 0
    }
  ]
}

Example output

{
  "count": 2,
  "items": [
    {
      "age": 50,
      "citation": {
        "authors": "Jawhar M, Schwaab J, Álvarez-Twose I, Shoumariyeh K, Naumann N, Lübke J, Perkins C, Muñoz-González JI, Meggendorfer M, Kennedy V, Metzgeroth G, Fabarius A, Pfeifer D, Sotlar K, Horny HP, von Bubnoff N, Haferlach T, Cross NCP, Hofmann WK, Sperr WR, García-Montero AC, Valent P, Gotlib J, Orfao A, Reiter A",
        "doi": "10.1200/JCO.19.00640",
        "id": "jawhar-2019",
        "pmid": "31509472",
        "source": "J Clin Oncol. 2019;37(31):2846-2856",
        "title": "MARS: Mutation-Adjusted Risk Score for Advanced Systemic Mastocytosis"
      },
      "components": [
        {
          "factor": "age_gt_60",
          "points": 0,
          "present": false,
          "value": 50
        },
        {
          "factor": "hemoglobin_lt_10",
          "points": 0,
          "present": false,
          "value": 12
        },
        {
          "factor": "platelets_lt_100",
          "points": 0,
          "present": false,
          "value": 200
        },
        {
          "factor": "sar_mutations",
          "points": 0,
          "present": false,
          "value": 0
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "formula": "mars",
      "formula_expression": "MARS = age_gt_60 1 + hemoglobin_lt_10 1 + platelets_lt_100 1 + sar_mutations (exactly one S/A/R 1, two or more 2; SRSF2, ASXL1, RUNX1); Jawhar 2019; max 5; low 0-1 (training-set median OS not reached), intermediate 2 (3.9 years), high 3-5 (1.9 years)",
      "hemoglobin_g_dl": 12,
      "max_score": 5,
      "platelets_10e9_l": 200,
      "risk_band": "low",
      "sar_mutation_count": 0,
      "score": 0
    },
    {
      "age": 50,
      "citation": {
        "authors": "Jawhar M, Schwaab J, Álvarez-Twose I, Shoumariyeh K, Naumann N, Lübke J, Perkins C, Muñoz-González JI, Meggendorfer M, Kennedy V, Metzgeroth G, Fabarius A, Pfeifer D, Sotlar K, Horny HP, von Bubnoff N, Haferlach T, Cross NCP, Hofmann WK, Sperr WR, García-Montero AC, Valent P, Gotlib J, Orfao A, Reiter A",
        "doi": "10.1200/JCO.19.00640",
        "id": "jawhar-2019",
        "pmid": "31509472",
        "source": "J Clin Oncol. 2019;37(31):2846-2856",
        "title": "MARS: Mutation-Adjusted Risk Score for Advanced Systemic Mastocytosis"
      },
      "components": [
        {
          "factor": "age_gt_60",
          "points": 0,
          "present": false,
          "value": 50
        },
        {
          "factor": "hemoglobin_lt_10",
          "points": 0,
          "present": false,
          "value": 12
        },
        {
          "factor": "platelets_lt_100",
          "points": 0,
          "present": false,
          "value": 200
        },
        {
          "factor": "sar_mutations",
          "points": 0,
       

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