75trust / 100

Calc Mipss70

by magent in Other

x402 APIPassing, checked 3 h ago

Guglielmelli 2018 MIPSS70 for transplant-age PMF: Hb <10 g/dL (1), leukocytes >25×10^9/L (2), platelets <100×10^9/L (2), blasts ≥2% (1), fibrosis ≥2 (1), symptoms (1), no type 1/like CALR (1), HMR category (1), ≥2 HMR (2); max 12. Low 0–1, intermediate 2–4, high ≥5. Italian-cohort median (5-year) OS 27.7 y (95%), 7.1 y (70%), 2.3 y (29%). Not MIPSS70-plus or version 2.0. magent does not sequence or grade marrow.

POST

https://api.magentlab.com/api/calc/mipss70

Price: $0.005; per call in USDC
Uptime: 100%; last 30 days
Response time: 308 ms; 1.3 s slowest 5%
Last check: Passed; 3 h ago, next any minute now

Run a free test call How to call it

Reliability

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Status and outage history · Atom feed · Watch with other listings

How to call it

POST https://api.magentlab.com/api/calc/mipss70

Each call costs $0.005 in USDC on Base, paid with the request over x402.

Run a free test callOne unpaid request, the way an agent sends it. You see the payment challenge it gets back. Nothing is charged.

Example request

From the listing.

POST https://api.magentlab.com/api/calc/mipss70
content-type: application/json

{
  "items": [
    {
      "blasts_percent": 0,
      "calr_type1_like": true,
      "constitutional_symptoms": false,
      "fibrosis_grade": 1,
      "hemoglobin_g_dl": 12,
      "hemoglobin_g_l": 120,
      "hmr_mutation_count": 0,
      "leukocytes_10e9_l": 10,
      "platelets_10e9_l": 200
    },
    {
      "blasts_percent": 0,
      "calr_type1_like": true,
      "constitutional_symptoms": false,
      "fibrosis_grade": 1,
      "hemoglobin_g_dl": 12,
      "hemoglobin_g_l": 120,
      "hmr_mutation_count": 0,
      "leukocytes_10e9_l": 10,
      "platelets_10e9_l": 200
    }
  ]
}

Parameters

Parameter	Type	Required	Description
`items`	array of object	Yes

Example response

The provider's example. We can't check it without paying.

Example response, 166 lines

{
  "count": 2,
  "items": [
    {
      "blasts_percent": 0,
      "calr_type1_like": true,
      "citation": {
        "authors": "Guglielmelli P, Lasho TL, Rotunno G, Mudireddy M, Mannarelli C, Nicolosi M, Pacilli A, Pardanani A, Rumi E, Rosti V, Hanson CA, Mannelli F, Ketterling RP, Gangat N, Rambaldi A, Passamonti F, Barosi G, Barbui T, Cazzola M, Vannucchi AM, Tefferi A",
        "doi": "10.1200/JCO.2017.76.4886",
        "id": "guglielmelli-2018",
        "pmid": "29226763",
        "source": "J Clin Oncol. 2018;36(4):310-318",
        "title": "MIPSS70: Mutation-Enhanced International Prognostic Score System for Transplantation-Age Patients With Primary Myelofibrosis"
      },
      "components": [
        {
          "factor": "hemoglobin_lt_10",
          "points": 0,
          "present": false,
          "value": 12
        },
        {
          "factor": "leukocytes_gt_25",
          "points": 0,
          "present": false,
          "value": 10
        },
        {
          "factor": "platelets_lt_100",
          "points": 0,
          "present": false,
          "value": 200
        },
        {
          "factor": "blasts_ge_2",
          "points": 0,
          "present": false,
          "value": 0
        },
        {
          "factor": "fibrosis_ge_2",
          "points": 0,
          "present": false,
          "value": 1
        },
        {
          "factor": "constitutional_symptoms",
          "points": 0,
          "present": false
        },
        {
          "factor": "absence_of_calr_type1_like",
          "points": 0,
          "present": false
        },
        {
          "factor": "hmr_category",
          "points": 0,
          "present": false,
          "value": 0
        },
        {
          "factor": "hmr_two_or_more",
          "points": 0,
          "present": false,
          "value": 0
        }
      ],
      "constitutional_symptoms": false,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "fibrosis_grade": 1,
      "five_year_survival_percent": 95,
      "formula": "mipss70",
      "formula_expression": "MIPSS70 = hemoglobin_lt_10 1 + leukocytes_gt_25 2 + platelets_lt_100 2 + blasts_ge_2 1 + fibrosis_ge_2 1 + constitutional_symptoms 1 + absence_of_calr_type1_like 1 + hmr_category 1 + hmr_two_or_more 2; Guglielmelli 2018; max 12; low 0-1, intermediate 2-4, high ≥5",
      "hemoglobin_g_dl": 12,
      "hmr_mutation_count": 0,
      "leukocytes_10e9_l": 10,
      "max_score": 12,
      "median_survival_years": 27.7,
      "platelets_10e9_l": 200,
      "risk_band": "low",
      "score": 0
    },
    {
      "blasts_percent": 0,
      "calr_type1_like": true,
      "citation": {
        "authors": "Guglielmelli P, Lasho TL, Rotunno G, Mudireddy M, Mannarelli C, Nicolosi M, Pacilli A, Pardanani A, Rumi E, Rosti V, Hanson CA, Mannelli F, Ketterling RP, Gangat N, Rambaldi A, Passamonti F, Barosi G, Barbui T, Cazzola M, Vannucchi AM, Tefferi A",
        "doi": "10.1200/JCO.2017.76.4886",
        "id": "guglielmelli-2018",
        "pmid": "29226763",
        "source": "J Clin Oncol. 2018;36(4):310-318",
        "title": "MIPSS70: Mutation-Enhanced International Prognostic Score System for Transplantation-Age Patients With Primary Myelofibrosis"
      },
      "components": [
        {
          "factor": "hemoglobin_lt_10",
          "points": 0,
          "present": false,
          "value": 12
        },
        {
          "factor": "leukocytes_gt_25",
          "points": 0,
          "present": false,
          "value": 10
        },
        {
          "factor": "platelets_lt_100",
          "points": 0,
          "present": false,
          "value": 200
        },
        {
          "factor": "blasts_ge_2",
          "points": 0,
          "present": false,
          "value": 0
        },
        {
          "factor": "fibrosis_ge_2",
          "points": 0,
          "present": false,
          "value": 1
        },
        {
          "factor": "constitutional_symptoms",
          "points": 0,
          "present": false
        },
        {
          "factor": "absence_of_calr_type1_like",
          "points": 0,
          "present": false
        },
        {
          "factor": "hmr_category",
          "points": 0,
          "present": false,
          "value": 0
        },
        {
          "factor": "hmr_two_or_more",
          "points": 0,
          "present": false,
          "value": 0
        }
      ],
      "constitutional_symptoms": false,
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "fibrosis_grade": 1,
      "five_year_survival_percent": 95,
      "formula": "mipss70",
      "formula_expression": "MIPSS70 = hemoglobin_lt_10 1 + leukocytes_gt_25 2 + platelets_lt_100 2 + blasts_ge_2 1 + fibrosis_ge_2 1 + constitutional_symptoms 1 + absence_of_calr_type1_like 1 + hmr_category 1 + hmr_two_or_more 2; Guglielmelli 2018; max 12; low 0-1, intermediate 2-4, high ≥5",
      "hemoglobin_g_dl": 12,
      "hmr_mutation_count": 0,
      "leukocytes_10e9_l": 10,
      "max_score": 12,
      "median_survival_years": 27.7,
      "platelets_10e9_l": 200,
      "risk_band": "low",
      "score": 0
    }
  ],
  "path": "/api/calc/mipss70"
}

Call it from code

The curl command shows the payment challenge. The JavaScript and Python versions pay and call, and never pay more than $0.005.

curl: see the payment challenge

# bash or zsh: see the payment challenge. Nothing is charged.
curl -sS -g -i -X POST 'https://api.magentlab.com/api/calc/mipss70' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"blasts_percent":0,"calr_type1_like":true,"constitutional_symptoms":false,"fibrosis_grade":1,"hemoglobin_g_dl":12,"hemoglobin_g_l":120,"hmr_mutation_count":0,"leukocytes_10e9_l":10,"platelets_10e9_l":200},{"blasts_percent":0,"calr_type1_like":true,"constitutional_symptoms":false,"fibrosis_grade":1,"hemoglobin_g_dl":12,"hemoglobin_g_l":120,"hmr_mutation_count":0,"leukocytes_10e9_l":10,"platelets_10e9_l":200}]}'

# x402 v2 sends the challenge base64-encoded in the PAYMENT-REQUIRED header (v1 sends it in the body).
# To read the header:
curl -sS -g -o /dev/null -D - -X POST 'https://api.magentlab.com/api/calc/mipss70' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"blasts_percent":0,"calr_type1_like":true,"constitutional_symptoms":false,"fibrosis_grade":1,"hemoglobin_g_dl":12,"hemoglobin_g_l":120,"hmr_mutation_count":0,"leukocytes_10e9_l":10,"platelets_10e9_l":200},{"blasts_percent":0,"calr_type1_like":true,"constitutional_symptoms":false,"fibrosis_grade":1,"hemoglobin_g_dl":12,"hemoglobin_g_l":120,"hmr_mutation_count":0,"leukocytes_10e9_l":10,"platelets_10e9_l":200}]}' \
  | grep -i '^payment-required:' | cut -d' ' -f2 | tr -d '\r' | base64 --decode

JavaScript: pay and call

// npm i @x402/fetch @x402/evm viem
import { wrapFetchWithPayment, x402Client } from "@x402/fetch";
import { registerExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";

// Pays at most $0.005 per call.
const client = new x402Client().setSpendControls({ maxAmountPerPayment: "$0.005" });
registerExactEvmScheme(client, { signer: privateKeyToAccount(process.env.EVM_PRIVATE_KEY) });
const pay = wrapFetchWithPayment(fetch, client);

// Not sure it's safe to pay? ToolVet checks it first for $0.005. Pay for that from a separate
// client: this one is capped at $0.005 per payment. GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Fapi.magentlab.com%2Fapi%2Fcalc%2Fmipss70&method=POST
const res = await pay("https://api.magentlab.com/api/calc/mipss70", {
  method: "POST",
  headers: { "content-type": "application/json" },
  body: JSON.stringify({
    "items": [
      {
        "blasts_percent": 0,
        "calr_type1_like": true,
        "constitutional_symptoms": false,
        "fibrosis_grade": 1,
        "hemoglobin_g_dl": 12,
        "hemoglobin_g_l": 120,
        "hmr_mutation_count": 0,
        "leukocytes_10e9_l": 10,
        "platelets_10e9_l": 200
      },
      {
        "blasts_percent": 0,
        "calr_type1_like": true,
        "constitutional_symptoms": false,
        "fibrosis_grade": 1,
        "hemoglobin_g_dl": 12,
        "hemoglobin_g_l": 120,
        "hmr_mutation_count": 0,
        "leukocytes_10e9_l": 10,
        "platelets_10e9_l": 200
      }
    ]
  }),
});
console.log(res.status, await res.text());

Python: pay and call

# pip install "x402[requests,evm]"
import os
from eth_account import Account
from x402 import x402ClientSync
from x402.http.clients import x402_requests
from x402.mechanisms.evm import EthAccountSigner
from x402.mechanisms.evm.exact.register import register_exact_evm_client

# Pays at most $0.005 per call.
client = x402ClientSync().set_spend_controls({"max_amount_per_payment": "$0.005"})
register_exact_evm_client(client, EthAccountSigner(Account.from_key(os.environ["EVM_PRIVATE_KEY"])))

with x402_requests(client) as session:
    res = session.post(
        "https://api.magentlab.com/api/calc/mipss70",
        json={
            "items": [
                {
                    "blasts_percent": 0,
                    "calr_type1_like": True,
                    "constitutional_symptoms": False,
                    "fibrosis_grade": 1,
                    "hemoglobin_g_dl": 12,
                    "hemoglobin_g_l": 120,
                    "hmr_mutation_count": 0,
                    "leukocytes_10e9_l": 10,
                    "platelets_10e9_l": 200,
                },
                {
                    "blasts_percent": 0,
                    "calr_type1_like": True,
                    "constitutional_symptoms": False,
                    "fibrosis_grade": 1,
                    "hemoglobin_g_dl": 12,
                    "hemoglobin_g_l": 120,
                    "hmr_mutation_count": 0,
                    "leukocytes_10e9_l": 10,
                    "platelets_10e9_l": 200,
                },
            ],
        },
    )
    print(res.status_code, res.text)

Security scan

No findings

We scan names, descriptions and tool definitions for hidden instructions and other prompt-injection patterns.

Recent checks

When	Result	HTTP	Time	Price
3 h ago	Passed	402	297 ms	$0.005
8 h ago	Passed	402	328 ms	$0.005
12 h ago	Passed	402	246 ms	$0.005
17 h ago	Passed	402	851 ms	$0.005
21 h ago	Passed	402	319 ms	$0.005

Show 10 older checks

25 h ago	Passed	402	405 ms	$0.005
29 h ago	Passed	402	2.2 s	$0.005
34 h ago	Passed	402	348 ms	$0.005
38 h ago	Passed	402	223 ms	$0.005
42 h ago	Passed	402	266 ms	$0.005
46 h ago	Passed	402	246 ms	$0.005
2 days ago	Passed	402	431 ms	$0.005
2 days ago	Passed	402	422 ms	$0.005
2 days ago	Passed	402	409 ms	$0.005
3 days ago	Passed	402	1.3 s	$0.005

Trust score 75/ 100

Availability (30-day uptime)		30 / 30
Valid x402 challenge		15 / 15
Response time		7 / 10
Real paying agents (30 days)		3 / 15
Charges what it lists		10 / 10
Security scan		10 / 10
Verified owner		0 / 10

How the score works

Payment terms

Price: $0.005 per call
Listed at: $0.005
Token: USDC
Networks: Base
Pays to: 0x836B…9Ee2

Real usage

Paying agents: 1 in 30 days
Paid calls: 3 in 30 days
Last paid call: 4 days ago

Source: x402 Bazaar settlement data.

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Trust score

[![ToolVet trust score](https://toolvet.app/badge/calc-mipss70.svg)](https://toolvet.app/s/calc-mipss70)