Calc R Iss
by magent in Security & trust
Palumbo 2015 R-ISS for multiple myeloma. ISS from beta-2 microglobulin and albumin (Greipp 2005). R-ISS I: ISS I, standard-risk iFISH CA, and normal LDH. R-ISS III: ISS III plus high-risk CA (del(17p) and/or t(4;14) and/or t(14;16)) or LDH > ULN. R-ISS II: all other combinations. Not a myeloma diagnosis or treatment choice; not R2-ISS; not Durie-Salmon. magent does not assay beta-2 microglobulin, albumin, LDH, or cytogenetics.
https://api.magentlab.com/api/calc/r_iss- Price
- $0.005
- per call in USDC
- Uptime
- 100%
- last 30 days
- Response time
- 222 ms
- 434 ms slowest 5%
- Last check
- Passed
- 39 min ago, next in 6 h
Reliability
Status and outage history · Atom feed · Watch with other listings
How to call it
GET https://api.magentlab.com/api/calc/r_iss
Each call costs $0.005 in USDC on Base, paid with the request over x402.
Run a free test callOne unpaid request, the way an agent sends it. You see the payment challenge it gets back. Nothing is charged.
Example request
From the listing.
GET https://api.magentlab.com/api/calc/r_iss?albumin_g_dl=4&albumin_g_l=40&beta2_microglobulin_mg_l=2&high_risk_ca=false&ldh_gt_uln=falseParameters
| Parameter | Type | Required | Description |
|---|---|---|---|
albumin_g_dl | number | No | Serum albumin in g/dL (1-6). Provide this or albumin_g_l, not both. ISS uses g/dL. Stage I requires albumin >= 3.5 when Sβ2M < 3.5. Ignored when Sβ2M >= 5.5. |
albumin_g_l | number | No | Serum albumin in g/L (10-60). Converted as g/dL = g/L / 10. Provide this or albumin_g_dl, not both. |
beta2_microglobulin_mg_l | number | Yes | Serum beta-2 microglobulin in mg/L (0.2-40). Greipp 2005 / Palumbo 2015 ISS. Stage I requires < 3.5; stage III when >= 5.5. magent does not assay beta-2 microglobulin. |
high_risk_ca | boolean | Yes | High-risk cytogenetic abnormalities as assigned by the caller: true iff del(17p) and/or t(4;14) and/or t(14;16) by iFISH (Palumbo 2015). magent does not FISH. |
ldh_gt_uln | boolean | Yes | Serum LDH greater than the upper limit of normal as assigned by the caller (Palumbo 2015: high LDH is > ULN). magent does not assay LDH or assign ULN. |
Example response
The provider's example. We can't check it without paying.
{
"albumin_g_dl": 4,
"beta2_microglobulin_mg_l": 2,
"citation": {
"authors": "Palumbo A, Avet-Loiseau H, Oliva S, et al.",
"doi": "10.1200/JCO.2015.61.2267",
"id": "palumbo-2015",
"pmid": "26240224",
"source": "J Clin Oncol. 2015;33(26):2863-2869",
"title": "Revised International Staging System for Multiple Myeloma: A Report From International Myeloma Working Group"
},
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"formula": "r_iss",
"formula_expression": "R-ISS I: ISS I AND high_risk_ca false AND ldh_gt_uln false; R-ISS III: ISS III AND (high_risk_ca OR ldh_gt_uln); R-ISS II: all other combinations. ISS I: beta2_microglobulin_mg_l < 3.5 AND albumin_g_dl >= 3.5; ISS III: beta2_microglobulin_mg_l >= 5.5; ISS II: neither I nor III (Palumbo 2015; ISS as Greipp 2005)",
"high_risk_ca": false,
"iss_stage": 1,
"iss_stage_label": "I",
"ldh_gt_uln": false,
"riss_stage": 1,
"riss_stage_label": "I"
}Call it from code
The curl command shows the payment challenge. The JavaScript and Python versions pay and call, and never pay more than $0.005.
curl: see the payment challenge
# bash or zsh: see the payment challenge. Nothing is charged.
curl -sS -g -i 'https://api.magentlab.com/api/calc/r_iss?albumin_g_dl=4&albumin_g_l=40&beta2_microglobulin_mg_l=2&high_risk_ca=false&ldh_gt_uln=false'
# x402 v2 sends the challenge base64-encoded in the PAYMENT-REQUIRED header (v1 sends it in the body).
# To read the header:
curl -sS -g -o /dev/null -D - 'https://api.magentlab.com/api/calc/r_iss?albumin_g_dl=4&albumin_g_l=40&beta2_microglobulin_mg_l=2&high_risk_ca=false&ldh_gt_uln=false' \
| grep -i '^payment-required:' | cut -d' ' -f2 | tr -d '\r' | base64 --decodeJavaScript: pay and call
// npm i @x402/fetch @x402/evm viem
import { wrapFetchWithPayment, x402Client } from "@x402/fetch";
import { registerExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";
// Pays at most $0.005 per call.
const client = new x402Client().setSpendControls({ maxAmountPerPayment: "$0.005" });
registerExactEvmScheme(client, { signer: privateKeyToAccount(process.env.EVM_PRIVATE_KEY) });
const pay = wrapFetchWithPayment(fetch, client);
// Not sure it's safe to pay? ToolVet checks it first for $0.005. Pay for that from a separate
// client: this one is capped at $0.005 per payment. GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Fapi.magentlab.com%2Fapi%2Fcalc%2Fr_iss
const res = await pay("https://api.magentlab.com/api/calc/r_iss?albumin_g_dl=4&albumin_g_l=40&beta2_microglobulin_mg_l=2&high_risk_ca=false&ldh_gt_uln=false");
console.log(res.status, await res.text());Python: pay and call
# pip install "x402[requests,evm]"
import os
from eth_account import Account
from x402 import x402ClientSync
from x402.http.clients import x402_requests
from x402.mechanisms.evm import EthAccountSigner
from x402.mechanisms.evm.exact.register import register_exact_evm_client
# Pays at most $0.005 per call.
client = x402ClientSync().set_spend_controls({"max_amount_per_payment": "$0.005"})
register_exact_evm_client(client, EthAccountSigner(Account.from_key(os.environ["EVM_PRIVATE_KEY"])))
with x402_requests(client) as session:
res = session.get("https://api.magentlab.com/api/calc/r_iss?albumin_g_dl=4&albumin_g_l=40&beta2_microglobulin_mg_l=2&high_risk_ca=false&ldh_gt_uln=false")
print(res.status_code, res.text)Security scan
No findings
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Recent checks
| When | Result | HTTP | Time | Price |
|---|---|---|---|---|
| 39 min ago | Passed | 402 | 222 ms | $0.005 |
| 11 h ago | Passed | 402 | 147 ms | $0.005 |
| 22 h ago | Passed | 402 | 434 ms | $0.005 |
| 31 h ago | Passed | 402 | 308 ms | $0.005 |
| 41 h ago | Passed | 402 | 282 ms | $0.005 |
Show 6 older checks
| 2 days ago | Passed | 402 | 166 ms | $0.005 |
| 3 days ago | Passed | 402 | 426 ms | $0.005 |
| 3 days ago | Passed | 402 | 143 ms | $0.005 |
| 3 days ago | Passed | 402 | 151 ms | $0.005 |
| 4 days ago | Passed | 402 | 364 ms | $0.005 |
| 4 days ago | Passed | 402 | 146 ms | $0.005 |