Calc Rema

{
  "count": 2,
  "items": [
    {
      "citation": {
        "authors": "Alvarez-Twose I, González-de-Olano D, Sánchez-Muñoz L, Matito A, Jara-Acevedo M, Teodosio C, García-Montero A, Morgado JM, Orfao A, Escribano L",
        "doi": "10.1159/000329856",
        "id": "alvarez-twose-2012",
        "pmid": "22042301",
        "source": "Int Arch Allergy Immunol. 2012;157(3):275-280 (Epub 2011 Oct 28)",
        "title": "Validation of the REMA score for predicting mast cell clonality and systemic mastocytosis in patients with systemic mast cell activation symptoms."
      },
      "clonality_likely": true,
      "components": [
        {
          "factor": "sex",
          "points": 1,
          "present": true,
          "value": "male"
        },
        {
          "factor": "tryptase_ug_l",
          "points": 2,
          "present": true,
          "value": 30
        },
        {
          "factor": "pruritus_hives_angioedema",
          "points": 1,
          "present": true
        },
        {
          "factor": "syncope_or_presyncope",
          "points": 3,
          "present": true
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "formula": "rema",
      "formula_expression": "REMA = sex (male +1, female −1) + tryptase_ug_l (<15 −1, 15–25 0, >25 +2) + pruritus_hives_angioedema (true −2, false +1) + syncope_or_presyncope (true +3, false 0); range −4 to +7; clonality_likely iff score >= 2 (Álvarez-Twose 2012)",
      "max_score": 7,
      "score": 7,
      "sex": "male",
      "tryptase_ug_l": 30
    },
    {
      "citation": {
        "authors": "Alvarez-Twose I, González-de-Olano D, Sánchez-Muñoz L, Matito A, Jara-Acevedo M, Teodosio C, García-Montero A, Morgado JM, Orfao A, Escribano L",
        "doi": "10.1159/000329856",
        "id": "alvarez-twose-2012",
        "pmid": "22042301",
        "source": "Int Arch Allergy Immunol. 2012;157(3):275-280 (Epub 2011 Oct 28)",
        "title": "Validation of the REMA score for predicting mast cell clonality and systemic mastocytosis in patients with systemic mast cell activation symptoms."
      },
      "clonality_likely": true,
      "components": [
        {
          "factor": "sex",
          "points": 1,
          "present": true,
          "value": "male"
        },
        {
          "factor": "tryptase_ug_l",
          "points": 2,
          "present": true,
          "value": 30
        },
        {
          "factor": "pruritus_hives_angioedema",
          "points": 1,
          "present": true
        },
        {
          "factor": "syncope_or_presyncope",
          "points": 3,
          "present": true
        }
      ],
      "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
      "formula": "rema",
      "formula_expression": "REMA = sex (male +1, female −1) + tryptase_ug_l (<15 −1, 15–25 0, >25 +2) + pruritus_hives_angioedema (true −2, false +1) + syncope_or_presyncope (true +3, false 0); range −4 to +7; clonality_likely iff score >= 2 (Álvarez-Twose 2012)",
      "max_score": 7,
      "score": 7,
      "sex": "male",
      "tryptase_ug_l": 30
    }
  ],
  "path": "/api/calc/rema"
}

# bash or zsh: see the payment challenge. Nothing is charged.
curl -sS -g -i -X POST 'https://api.magentlab.com/api/calc/rema' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"pruritus_hives_angioedema":false,"sex":"male","syncope_or_presyncope":true,"tryptase_ug_l":30},{"pruritus_hives_angioedema":false,"sex":"male","syncope_or_presyncope":true,"tryptase_ug_l":30}]}'

# x402 v2 sends the challenge base64-encoded in the PAYMENT-REQUIRED header (v1 sends it in the body).
# To read the header:
curl -sS -g -o /dev/null -D - -X POST 'https://api.magentlab.com/api/calc/rema' \
  -H 'content-type: application/json' \
  --data-raw '{"items":[{"pruritus_hives_angioedema":false,"sex":"male","syncope_or_presyncope":true,"tryptase_ug_l":30},{"pruritus_hives_angioedema":false,"sex":"male","syncope_or_presyncope":true,"tryptase_ug_l":30}]}' \
  | grep -i '^payment-required:' | cut -d' ' -f2 | tr -d '\r' | base64 --decode

// npm i @x402/fetch @x402/evm viem
import { wrapFetchWithPayment, x402Client } from "@x402/fetch";
import { registerExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";

// Pays at most $0.007 per call.
const client = new x402Client().setSpendControls({ maxAmountPerPayment: "$0.007" });
registerExactEvmScheme(client, { signer: privateKeyToAccount(process.env.EVM_PRIVATE_KEY) });
const pay = wrapFetchWithPayment(fetch, client);

// Not sure it's safe to pay? ToolVet checks it first for $0.005. Pay for that from a separate
// client: this one is capped at $0.007 per payment. GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Fapi.magentlab.com%2Fapi%2Fcalc%2Frema&method=POST
const res = await pay("https://api.magentlab.com/api/calc/rema", {
  method: "POST",
  headers: { "content-type": "application/json" },
  body: JSON.stringify({
    "items": [
      {
        "pruritus_hives_angioedema": false,
        "sex": "male",
        "syncope_or_presyncope": true,
        "tryptase_ug_l": 30
      },
      {
        "pruritus_hives_angioedema": false,
        "sex": "male",
        "syncope_or_presyncope": true,
        "tryptase_ug_l": 30
      }
    ]
  }),
});
console.log(res.status, await res.text());

# pip install "x402[requests,evm]"
import os
from eth_account import Account
from x402 import x402ClientSync
from x402.http.clients import x402_requests
from x402.mechanisms.evm import EthAccountSigner
from x402.mechanisms.evm.exact.register import register_exact_evm_client

# Pays at most $0.007 per call.
client = x402ClientSync().set_spend_controls({"max_amount_per_payment": "$0.007"})
register_exact_evm_client(client, EthAccountSigner(Account.from_key(os.environ["EVM_PRIVATE_KEY"])))

with x402_requests(client) as session:
    res = session.post(
        "https://api.magentlab.com/api/calc/rema",
        json={
            "items": [
                {
                    "pruritus_hives_angioedema": False,
                    "sex": "male",
                    "syncope_or_presyncope": True,
                    "tryptase_ug_l": 30,
                },
                {
                    "pruritus_hives_angioedema": False,
                    "sex": "male",
                    "syncope_or_presyncope": True,
                    "tryptase_ug_l": 30,
                },
            ],
        },
    )
    print(res.status_code, res.text)