Calc Who Sm
by magent in Other
WHO 2016 systemic mastocytosis (Valent 2016 Table 1). Met when major infiltrates (≥15 mast cells in aggregates in BM or extracutaneous organ) plus ≥1 minor, or ≥3 minors. Minors: >25% atypical/spindle mast cells, KIT codon 816, CD2 and/or CD25, tryptase >20 ng/mL (not valid with an unrelated myeloid neoplasm). Not a diagnosis. Not cutaneous mastocytosis only. Not ICC 2022. magent does not read a biopsy or assay tryptase.
https://api.magentlab.com/api/calc/who_sm- Price
- $0.005
- per call in USDC
- Uptime
- 100%
- last 30 days
- Response time
- 221 ms
- 986 ms slowest 5%
- Last check
- Passed
- 37 min ago, next any minute now
Reliability
Status and outage history · Atom feed · Watch with other listings
How to call it
GET https://api.magentlab.com/api/calc/who_sm
Each call costs $0.005 in USDC on Base, paid with the request over x402.
Run a free test callOne unpaid request, the way an agent sends it. You see the payment challenge it gets back. Nothing is charged.
Example request
From the listing.
GET https://api.magentlab.com/api/calc/who_sm?associated_myeloid_neoplasm=false&atypical_or_spindle=false&cd2_or_cd25=false&kit_codon_816=true&major_infiltrates=true&tryptase_gt_20=falseParameters
| Parameter | Type | Required | Description |
|---|---|---|---|
associated_myeloid_neoplasm | boolean | Yes | Unrelated myeloid neoplasm present as assigned by the caller (Valent 2016 Table 1: item d is not valid). When true, tryptase_gt_20 does not count as a minor. true or false. magent does not diagnose a myeloid neoplasm. |
atypical_or_spindle | boolean | Yes | >25% atypical (type I/II) or spindle-shaped mast cells in infiltrates or smears, as assigned by the caller (Valent 2016 Table 1 minor a). true or false. magent does not read slides. |
cd2_or_cd25 | boolean | Yes | Mast cells in bone marrow, blood, or another extracutaneous organ exhibit CD2 and/or CD25, as assigned by the caller (Valent 2016 Table 1 minor c). true or false. magent does not phenotype mast cells. |
kit_codon_816 | boolean | Yes | KIT point mutation at codon 816 in bone marrow or another extracutaneous organ, as assigned by the caller (Valent 2016 Table 1 minor b). true or false. magent does not sequence KIT. |
major_infiltrates | boolean | Yes | Multifocal dense infiltrates of mast cells (≥15 MCs in aggregates) in bone marrow or another extracutaneous organ, as assigned by the caller (Valent 2016 Table 1 major). true or false. magent does not read a biopsy. |
tryptase_gt_20 | boolean | Yes | Baseline serum tryptase >20 ng/mL as assigned by the caller (Valent 2016 Table 1 minor d). Does not count when associated_myeloid_neoplasm is true. true or false. magent does not assay tryptase. |
Example response
The provider's example. We can't check it without paying.
Example response, 57 lines
{
"associated_myeloid_neoplasm": false,
"atypical_or_spindle": false,
"cd2_or_cd25": false,
"citation": {
"authors": "Valent P, Akin C, Hartmann K, Nilsson G, Reiter A, Hermine O, Sotlar K, Sperr WR, Escribano L, George TI, Kluin-Nelemans HC, Ustun C, Triggiani M, Brockow K, Gotlib J, Orfao A, Schwartz LB, Horny HP, Galli SJ, Arock M, Metcalfe DD",
"doi": "10.1182/blood-2016-09-731893",
"id": "valent-2016",
"pmid": "28031180",
"source": "Blood. 2017;129(11):1420-1427 (Epub 2016 Dec 28)",
"title": "Mastocytosis: 2016 updated WHO classification and novel emerging treatment concepts"
},
"criteria": [
{
"factor": "major",
"met": true
},
{
"factor": "atypical_or_spindle",
"met": false
},
{
"factor": "kit_codon_816",
"met": true
},
{
"factor": "cd2_or_cd25",
"met": false
},
{
"factor": "tryptase_counts",
"met": false
},
{
"factor": "associated_myeloid_neoplasm",
"met": false
},
{
"factor": "minor_count_ge_1",
"met": true
},
{
"factor": "minor_count_ge_3",
"met": false
}
],
"diagnosed": true,
"disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
"formula": "who_sm",
"formula_expression": "diagnosed iff (major_infiltrates and minor_count ≥ 1) or minor_count ≥ 3; minor_count counts atypical_or_spindle, kit_codon_816, cd2_or_cd25, and tryptase_gt_20 only when associated_myeloid_neoplasm is false (Valent 2016 Table 1 WHO SM). Not a diagnosis. Not cutaneous mastocytosis only. Not ICC 2022",
"kit_codon_816": true,
"major": true,
"major_infiltrates": true,
"minor_count": 1,
"tryptase_counts": false,
"tryptase_gt_20": false
}Call it from code
The curl command shows the payment challenge. The JavaScript and Python versions pay and call, and never pay more than $0.005.
curl: see the payment challenge
# bash or zsh: see the payment challenge. Nothing is charged.
curl -sS -g -i 'https://api.magentlab.com/api/calc/who_sm?associated_myeloid_neoplasm=false&atypical_or_spindle=false&cd2_or_cd25=false&kit_codon_816=true&major_infiltrates=true&tryptase_gt_20=false'
# x402 v2 sends the challenge base64-encoded in the PAYMENT-REQUIRED header (v1 sends it in the body).
# To read the header:
curl -sS -g -o /dev/null -D - 'https://api.magentlab.com/api/calc/who_sm?associated_myeloid_neoplasm=false&atypical_or_spindle=false&cd2_or_cd25=false&kit_codon_816=true&major_infiltrates=true&tryptase_gt_20=false' \
| grep -i '^payment-required:' | cut -d' ' -f2 | tr -d '\r' | base64 --decodeJavaScript: pay and call
// npm i @x402/fetch @x402/evm viem
import { wrapFetchWithPayment, x402Client } from "@x402/fetch";
import { registerExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";
// Pays at most $0.005 per call.
const client = new x402Client().setSpendControls({ maxAmountPerPayment: "$0.005" });
registerExactEvmScheme(client, { signer: privateKeyToAccount(process.env.EVM_PRIVATE_KEY) });
const pay = wrapFetchWithPayment(fetch, client);
// Not sure it's safe to pay? ToolVet checks it first for $0.005. Pay for that from a separate
// client: this one is capped at $0.005 per payment. GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Fapi.magentlab.com%2Fapi%2Fcalc%2Fwho_sm
const res = await pay("https://api.magentlab.com/api/calc/who_sm?associated_myeloid_neoplasm=false&atypical_or_spindle=false&cd2_or_cd25=false&kit_codon_816=true&major_infiltrates=true&tryptase_gt_20=false");
console.log(res.status, await res.text());Python: pay and call
# pip install "x402[requests,evm]"
import os
from eth_account import Account
from x402 import x402ClientSync
from x402.http.clients import x402_requests
from x402.mechanisms.evm import EthAccountSigner
from x402.mechanisms.evm.exact.register import register_exact_evm_client
# Pays at most $0.005 per call.
client = x402ClientSync().set_spend_controls({"max_amount_per_payment": "$0.005"})
register_exact_evm_client(client, EthAccountSigner(Account.from_key(os.environ["EVM_PRIVATE_KEY"])))
with x402_requests(client) as session:
res = session.get("https://api.magentlab.com/api/calc/who_sm?associated_myeloid_neoplasm=false&atypical_or_spindle=false&cd2_or_cd25=false&kit_codon_816=true&major_infiltrates=true&tryptase_gt_20=false")
print(res.status_code, res.text)Security scan
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Recent checks
| When | Result | HTTP | Time | Price |
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