Pubmed Search

{
  "query": "GLP-1 obesity",
  "results": [
    {
      "abstract": "Thanks to biochemical engineering, the glucagon-like peptide-1 (GLP-1) molecule has emerged as an essential element in the development of diverse agonists and multiagonists, based in the GLP-1 structure for obesity treatment. These new antiobesity medications can reach up to 24% weight loss, which makes possible an effective management of obesity and its complications. GLP-1 agonists affect divers…",
      "authors": [
        "Salvador J"
      ],
      "doi": "10.1016/j.medcli.2025.107035",
      "journal": "Medicina clinica",
      "pmid": "40466247",
      "pubDate": "2025 Jul",
      "title": "GLP-1-based medications: Mechanisms involved in obesity treatment.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/40466247/"
    },
    {
      "abstract": "Glucagon-like peptide-1 receptor agonists (GLP1RA) augment glucose-dependent insulin release and reduce glucagon secretion and gastric emptying, enabling their successful development for the treatment of type 2 diabetes (T2D). These agents also inhibit food intake and reduce body weight, fostering investigation of GLP1RA for the treatment of obesity. Here I discuss the physiology of Glucagon-like …",
      "authors": [
        "Drucker DJ"
      ],
      "doi": "10.1016/j.molmet.2021.101351",
      "journal": "Molecular metabolism",
      "pmid": "34626851",
      "pubDate": "2022 Mar",
      "title": "GLP-1 physiology informs the pharmacotherapy of obesity.",
      "url": "https://pubmed.ncbi.nlm.nih.gov/34626851/"
    }
  ],
  "source": "NCBI PubMed E-utilities",
  "total": 11811
}

# bash or zsh: see the payment challenge. Nothing is charged.
curl -sS -g -i -X POST 'https://lumenworks-x402-decoder.onrender.com/v1/pubmed/search' \
  -H 'content-type: application/json' \
  --data-raw '{"limit":2,"query":"GLP-1 obesity"}'

# x402 v2 sends the challenge base64-encoded in the PAYMENT-REQUIRED header (v1 sends it in the body).
# To read the header:
curl -sS -g -o /dev/null -D - -X POST 'https://lumenworks-x402-decoder.onrender.com/v1/pubmed/search' \
  -H 'content-type: application/json' \
  --data-raw '{"limit":2,"query":"GLP-1 obesity"}' \
  | grep -i '^payment-required:' | cut -d' ' -f2 | tr -d '\r' | base64 --decode

// npm i @x402/fetch @x402/evm viem
import { wrapFetchWithPayment, x402Client } from "@x402/fetch";
import { registerExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";

// Pays at most $0.001 per call.
const client = new x402Client().setSpendControls({ maxAmountPerPayment: "$0.001" });
registerExactEvmScheme(client, { signer: privateKeyToAccount(process.env.EVM_PRIVATE_KEY) });
const pay = wrapFetchWithPayment(fetch, client);

// Not sure it's safe to pay? ToolVet checks it first for $0.005. Pay for that from a separate
// client: this one is capped at $0.001 per payment. GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Flumenworks-x402-decoder.onrender.com%2Fv1%2Fpubmed%2Fsearch&method=POST
const res = await pay("https://lumenworks-x402-decoder.onrender.com/v1/pubmed/search", {
  method: "POST",
  headers: { "content-type": "application/json" },
  body: JSON.stringify({
    "limit": 2,
    "query": "GLP-1 obesity"
  }),
});
console.log(res.status, await res.text());

# pip install "x402[requests,evm]"
import os
from eth_account import Account
from x402 import x402ClientSync
from x402.http.clients import x402_requests
from x402.mechanisms.evm import EthAccountSigner
from x402.mechanisms.evm.exact.register import register_exact_evm_client

# Pays at most $0.001 per call.
client = x402ClientSync().set_spend_controls({"max_amount_per_payment": "$0.001"})
register_exact_evm_client(client, EthAccountSigner(Account.from_key(os.environ["EVM_PRIVATE_KEY"])))

with x402_requests(client) as session:
    res = session.post(
        "https://lumenworks-x402-decoder.onrender.com/v1/pubmed/search",
        json={
            "limit": 2,
            "query": "GLP-1 obesity",
        },
    )
    print(res.status_code, res.text)