Pubmed Search

{
  "articles": [
    {
      "authors": [
        "Nejatinejad M",
        "Maleki-Aram A"
      ],
      "date": "2027 Jan",
      "doi": "10.1016/j.cca.2026.121178",
      "journal": "Clinica chimica acta; international journal of clinical chemistry",
      "link": "https://pubmed.ncbi.nlm.nih.gov/42285341/",
      "pmid": "42285341",
      "summary": "BRAF mutations are key oncogenic alterations across multiple malignancies, including melanoma, thyroid carcinoma, colorectal cancer, non-small cell lung cancer, glioma, and hairy cell leukemia. The most prevalent variant, BRAF-V600E, induces constitutive activation of the MAPK signaling pathway, pro…",
      "title": "Molecular Landscape and Advanced Diagnostic Technologies for BRAF Mutations in Cancer: From Quantitative PCR and ddPCR to CRISPR-Based Platforms."
    },
    {
      "authors": [
        "Avershina E",
        "Birkeland EE"
      ],
      "date": "2026 Dec",
      "doi": "10.1080/19490976.2026.2734649",
      "journal": "Gut microbes",
      "link": "https://pubmed.ncbi.nlm.nih.gov/42768305/",
      "pmid": "42768305",
      "summary": "Bacteria in the human gut influence host physiology and disease risk, but their ecology is strongly shaped by mobile genetic elements (MGEs) such as phages and plasmids. Past interactions between bacteria and MGEs can be inferred from CRISPR-Cas cassettes, which contain short DNA fragments derived f…",
      "title": "CRISPR-Cas immune repertoires as an ecological record of bacterial interactions with mobile genetic elements in the human gut."
    }
  ],
  "query": "crispr cancer",
  "source": "PubMed (NCBI/NLM, EE. UU.)",
  "total": 18230
}

# bash or zsh: see the payment challenge. Nothing is charged.
curl -sS -g -i -X POST 'https://api.vextorium.com/v1/pubmed-search' \
  -H 'content-type: application/json' \
  --data-raw '{"limit":2,"query":"crispr cancer"}'

# x402 v2 sends the challenge base64-encoded in the PAYMENT-REQUIRED header (v1 sends it in the body).
# To read the header:
curl -sS -g -o /dev/null -D - -X POST 'https://api.vextorium.com/v1/pubmed-search' \
  -H 'content-type: application/json' \
  --data-raw '{"limit":2,"query":"crispr cancer"}' \
  | grep -i '^payment-required:' | cut -d' ' -f2 | tr -d '\r' | base64 --decode

// npm i @x402/fetch @x402/evm viem
import { wrapFetchWithPayment, x402Client } from "@x402/fetch";
import { registerExactEvmScheme } from "@x402/evm/exact/client";
import { privateKeyToAccount } from "viem/accounts";

// Pays at most $0.003 per call.
const client = new x402Client().setSpendControls({ maxAmountPerPayment: "$0.003" });
registerExactEvmScheme(client, { signer: privateKeyToAccount(process.env.EVM_PRIVATE_KEY) });
const pay = wrapFetchWithPayment(fetch, client);

// Not sure it's safe to pay? ToolVet checks it first for $0.005. Pay for that from a separate
// client: this one is capped at $0.003 per payment. GET https://toolvet.app/api/v1/check?url=https%3A%2F%2Fapi.vextorium.com%2Fv1%2Fpubmed-search&method=POST
const res = await pay("https://api.vextorium.com/v1/pubmed-search", {
  method: "POST",
  headers: { "content-type": "application/json" },
  body: JSON.stringify({
    "limit": 2,
    "query": "crispr cancer"
  }),
});
console.log(res.status, await res.text());

# pip install "x402[requests,evm]"
import os
from eth_account import Account
from x402 import x402ClientSync
from x402.http.clients import x402_requests
from x402.mechanisms.evm import EthAccountSigner
from x402.mechanisms.evm.exact.register import register_exact_evm_client

# Pays at most $0.003 per call.
client = x402ClientSync().set_spend_controls({"max_amount_per_payment": "$0.003"})
register_exact_evm_client(client, EthAccountSigner(Account.from_key(os.environ["EVM_PRIVATE_KEY"])))

with x402_requests(client) as session:
    res = session.post(
        "https://api.vextorium.com/v1/pubmed-search",
        json={
            "limit": 2,
            "query": "crispr cancer",
        },
    )
    print(res.status_code, res.text)